OBJECTIVE: Soybeans, an excellent source of dietary peptides, have beneficial effects on health. We investigated the effect of the soybean peptide on immune function, brain function, and neurochemistry in healthy volunteers. METHODS: Near-infrared spectroscopy (NIRS) was used to analyze brain cerebral blood flow. The A and DA levels in the serum were analyzed by ELISA kit. The total number of leukocytes was recorded with a standard counter. Flow cytometry was used to assess lymphocyte subset levels. RESULTS: Cell numbers were upregulated in the group that had fewer leukocytes but downregulated in the group with more leukocytes. For the lymphocyte-rich type, lymphocyte counts tended to decrease, accompanied by an increase in granulocyte numbers. For the granulocyte-rich type, granulocyte counts tended to increase, but lymphocyte counts also increased. The numbers of CD11b(+) cells and CD56(+) cells increased significantly. Soybean peptide decreased the adrenalin level in plasma but increased the level of dopamine. Near-infrared spectroscopy showed significant increases in the amplitudes of θ, α-2, and β-L frequency bands after the ingestion of peptides. CONCLUSION: Soybean peptides can modulate cellular immune systems, regulate neurotransmitters, and boost brain function.
OBJECTIVE:Soybeans, an excellent source of dietary peptides, have beneficial effects on health. We investigated the effect of the soybean peptide on immune function, brain function, and neurochemistry in healthy volunteers. METHODS: Near-infrared spectroscopy (NIRS) was used to analyze brain cerebral blood flow. The A and DA levels in the serum were analyzed by ELISA kit. The total number of leukocytes was recorded with a standard counter. Flow cytometry was used to assess lymphocyte subset levels. RESULTS: Cell numbers were upregulated in the group that had fewer leukocytes but downregulated in the group with more leukocytes. For the lymphocyte-rich type, lymphocyte counts tended to decrease, accompanied by an increase in granulocyte numbers. For the granulocyte-rich type, granulocyte counts tended to increase, but lymphocyte counts also increased. The numbers of CD11b(+) cells and CD56(+) cells increased significantly. Soybean peptide decreased the adrenalin level in plasma but increased the level of dopamine. Near-infrared spectroscopy showed significant increases in the amplitudes of θ, α-2, and β-L frequency bands after the ingestion of peptides. CONCLUSION:Soybean peptides can modulate cellular immune systems, regulate neurotransmitters, and boost brain function.
Authors: D Val-Laillet; E Aarts; B Weber; M Ferrari; V Quaresima; L E Stoeckel; M Alonso-Alonso; M Audette; C H Malbert; E Stice Journal: Neuroimage Clin Date: 2015-03-24 Impact factor: 4.881
Authors: Srichandan Padhi; Samurailatpam Sanjukta; Rounak Chourasia; Rajendra K Labala; Sudhir P Singh; Amit K Rai Journal: Front Mol Biosci Date: 2021-03-31
Authors: Kashaf Junaid; Hasan Ejaz; Abualgasim Elgaili Abdalla; Khalid O A Abosalif; Muhammad Ikram Ullah; Humaira Yasmeen; Sonia Younas; Sanaa S M Hamam; Abdul Rehman Journal: Nutrients Date: 2020-09-29 Impact factor: 5.717