Literature DB >> 21871598

Fetopathologic examination for early termination of pregnancy: dogma or necessity?

Laurence Gitz1, Suonavy Khung-Savatovsky, Géraldine Viot, Julia Tantau, Gilles Grangé, Fanny Lewin, Anne-Lise Delezoide, Jean-François Oury, Vassilis Tsatsaris.   

Abstract

OBJECTIVE: Our objective was assessment of fetopathological examination after termination of pregnancy (TOP) for fetal anomalies with normal karyotype <17 weeks of gestation. STUDY
DESIGN: This was a multicenter retrospective study. Records of TOP for fetal anomalies with normal karyotype were analyzed. Primary outcomes were modifications of genetic counseling and management of next subsequent pregnancies. Medical TOPs were compared with surgical TOPs.
RESULTS: In all, 59 pregnancies were included (30 aspirations, 29 inductions). Fetopathological examination modified genetic counseling for 22 patients: 62% for the medical induction group vs 13% in the vacuum aspiration group (P < .001). Management of subsequent pregnancies was modified in 17% in the medical induction group vs 3% in the aspiration group (P = .06).
CONCLUSION: Fetopathological examination for early TOP with normal karyotype is relevant, especially when an intact fetus is examined. Thanks to it, genetic counseling is often modified, as is management of the next pregnancy. Medical procedures should be preferred to surgical procedures.
Copyright © 2011 Mosby, Inc. All rights reserved.

Entities:  

Mesh:

Year:  2011        PMID: 21871598     DOI: 10.1016/j.ajog.2011.06.066

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  1 in total

1.  Diagnostic value of fetal autopsy after early termination of pregnancy for fetal anomalies.

Authors:  Violaine Peyronnet; Olivia Anselem; Laurence Loeuillet; Nathalie Roux; Vassilis Tsatsaris
Journal:  PLoS One       Date:  2022-10-19       Impact factor: 3.752

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.