Literature DB >> 21868591

Evaluation of the precision of emergency department diagnoses in young children with fever.

Joshua M Colvin1, David M Jaffe, Jared T Muenzer.   

Abstract

OBJECTIVE. To characterize causes of fever in children presenting to a pediatric emergency department (ED). METHODS. One-year retrospective review of ED records. Inclusion criteria were 2 to 36 months of age with a documented temperature ≥ 39°C. Exclusion criteria were elopement, repeat visit, and underlying diagnosis with a predisposition to infection. Medical records were reviewed using a predefined, study-specific, data abstraction tool. Based on diagnosis and pathogen detection, visits were assigned to 3 groups, laboratory confirmed pathogen and focal or nonfocal diagnosis without confirmed pathogen. RESULTS. A total of 1091 visits met inclusion criteria. Fourteen percent had a pathogen detected, 56% had a focal diagnosis without a confirmed pathogen, and 30% had a nonfocal diagnosis without confirmed pathogen. CONCLUSIONS. In a cohort of febrile children 2 to 36 months of age, only 14% had a confirmed pathogen. New rapid viral diagnostic techniques may provide an opportunity to improve diagnostic certainty in young children presenting with fever.

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Year:  2011        PMID: 21868591      PMCID: PMC4354802          DOI: 10.1177/0009922811417295

Source DB:  PubMed          Journal:  Clin Pediatr (Phila)        ISSN: 0009-9228            Impact factor:   1.168


  22 in total

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4.  Bacteremia in febrile children seen in a "walk-in" pediatric clinic.

Authors:  J E McGowan; L Bratton; J O Klein; M Finland
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5.  Diagnosis and outcomes of enterovirus infections in young infants.

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Journal:  Pediatr Infect Dis J       Date:  2005-06       Impact factor: 2.129

6.  Epidemiology and laboratory diagnosis of infection with viral and bacterial pathogens in infants hospitalized for suspected sepsis.

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7.  Serious bacterial infections in febrile infants in the post-pneumococcal conjugate vaccine era.

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8.  Antibiotic administration to treat possible occult bacteremia in febrile children.

Authors:  D M Jaffe; R R Tanz; A T Davis; F Henretig; G Fleisher
Journal:  N Engl J Med       Date:  1987-11-05       Impact factor: 91.245

9.  Adenoviral infections in children: the impact of rapid diagnosis.

Authors:  Christian Rocholl; Kris Gerber; Judy Daly; Andrew T Pavia; Carrie L Byington
Journal:  Pediatrics       Date:  2004-01       Impact factor: 7.124

10.  Primary human herpesvirus 6 infection in young children.

Authors:  P Pruksananonda; C B Hall; R A Insel; K McIntyre; P E Pellett; C E Long; K C Schnabel; P H Pincus; F R Stamey; T R Dambaugh
Journal:  N Engl J Med       Date:  1992-05-28       Impact factor: 91.245

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2.  Detection of viruses in young children with fever without an apparent source.

Authors:  Joshua M Colvin; Jared T Muenzer; David M Jaffe; Avraham Smason; Elena Deych; William D Shannon; Max Q Arens; Richard S Buller; Wai-Ming Lee; Erica J Sodergren Weinstock; George M Weinstock; Gregory A Storch
Journal:  Pediatrics       Date:  2012-11-05       Impact factor: 7.124

  2 in total

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