Literature DB >> 21867546

Carotid angiodysplasia complicated by the use of anti-hypertensive drugs during pregnancy: a case report.

Viviane Ribeiro de Paula1, Laura Penna Rocha, Giovanni Carlos Tiveron, Camila Souza de Oliveira Guimarães, Marlene Antônia Dos Reis, Beatriz Barco Tavares, Rosana Rosa Miranda Corrêa.   

Abstract

INTRODUCTION: Hypertensive syndromes in pregnancy are one of the leading causes of obstetric admissions into intensive care units. They are related to changes in the central nervous system caused by a decrease in cerebral perfusion pressure, indicated by an increase in intracranial pressure. These changes in pressure usually result from acute injuries or a decrease in the mean arterial pressure due to iatrogenic action or shock. However, other vascular disorders may contribute to similar occurrences. CASE
PRESENTATION: A 15-year-old girl was admitted to our hospital complaining of severe headaches since the eighth month of pregnancy, and presented with an arterial blood pressure of 180/120 mmHg. The diagnostic hypothesis was pre-eclampsia. Our patient's blood pressure levels remained elevated, and she was submitted to a cesarean section. After the procedure, she was referred to our infirmary, presenting with a blank distant look and with no interaction with the environment, dyslalia, and labial and upper and lower right limb paresis. She was confused and unable to speak, but responded to painful stimuli as she conveyed abdominal pain at superficial and deep palpation. The hypothesis of post-partum psychosis was suggested. She was then transferred to our intensive care unit, maintaining an impassive attitude in bed but reacting to external stimuli. Results of a computed tomography scan revealed ischemic infarction of the territory of her left middle cerebral artery. A selective cerebral arteriography showed bilateral occlusion of her internal carotid artery in the intracranial position, prebifurcation and angiodysplasia in the cervical segments of her internal carotid artery. Sixteen days after hospital admission, our patient died.
CONCLUSION: This data shows the need for careful monitoring of hypertensive syndromes in pregnancy cases, especially in cases with a history of chronic hypertension or with vascular alterations, It also highlights the need for constant supervision of blood pressure levels during the use of anti-hypertensive medications.

Entities:  

Year:  2011        PMID: 21867546      PMCID: PMC3174930          DOI: 10.1186/1752-1947-5-415

Source DB:  PubMed          Journal:  J Med Case Rep        ISSN: 1752-1947


  7 in total

1.  Cerebral vascular adaptation to pregnancy and its role in the neurological complications of eclampsia.

Authors:  Marilyn J Cipolla; Julie G Sweet; Siu-Lung Chan
Journal:  J Appl Physiol (1985)       Date:  2010-11-11

Review 2.  Interventions for the prevention and treatment of postpartum psychosis: a systematic review.

Authors:  Shelley Doucet; Ian Jones; Nicole Letourneau; Cindy-Lee Dennis; Emma Robertson Blackmore
Journal:  Arch Womens Ment Health       Date:  2010-12-03       Impact factor: 3.633

3.  Effects of age and coronary artery disease on cerebrovascular reactivity to carbon dioxide in humans.

Authors:  S D Galvin; L A Celi; K N Thomas; T R Clendon; I F Galvin; R W Bunton; P N Ainslie
Journal:  Anaesth Intensive Care       Date:  2010-07       Impact factor: 1.669

4.  Is intensive care the only answer for high risk pregnancies in developing nations?

Authors:  Sukhwinder Kaur Bajwa; Sukhminder Jit Singh Bajwa; Jasbir Kaur; Kamaljit Singh; Jasleen Kaur
Journal:  J Emerg Trauma Shock       Date:  2010-10

5.  Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics.

Authors:  J B Mulliken; J Glowacki
Journal:  Plast Reconstr Surg       Date:  1982-03       Impact factor: 4.730

6.  Placental morphometrical and histopathology changes in the different clinical presentations of hypertensive syndromes in pregnancy.

Authors:  Rosana R M Corrêa; Daniel B Gilio; Camila L Cavellani; Marina C Paschoini; Flávia A Oliveira; Luís C Peres; Marlene A Reis; Vicente P A Teixeira; Eumenia C C Castro
Journal:  Arch Gynecol Obstet       Date:  2007-09-05       Impact factor: 2.344

Review 7.  Neurologic complications of pre-eclampsia.

Authors:  Gerda G Zeeman
Journal:  Semin Perinatol       Date:  2009-06       Impact factor: 3.300

  7 in total

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