Literature DB >> 21867478

Gene patents related to common diseases of the eye.

Srujana Sahebjada1, Stuart Cantsileris, Paul N Baird.   

Abstract

Visual impairment and blindness impose substantial morbidity and premature mortality on the population. The direct costs for vision disorders have been shown to be more than the cost of coronary heart disease, stroke, arthritis or depression and were estimated to be $9.85 billion in 2004 in Australia. Hence it is important to identify the causes of common eye diseases and understand their aetiology which in turn would allow determination of better management strategies and treatment options. Age related Macular Degeneration, Cataract, Diabetic Retinopathy, Glaucoma and uncorrected refractive errors represent the majority of the visual impairment and blindness in Australia and various parts of the world. This article reviews the gene patents available for these eye conditions and highlights the important discoveries that have so far contributed to our understanding of these diseases and provides valuable information as to where research will be heading in the future.

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Year:  2011        PMID: 21867478     DOI: 10.2174/187221511797636239

Source DB:  PubMed          Journal:  Recent Pat DNA Gene Seq        ISSN: 1872-2156


  3 in total

Review 1.  The complement system in age-related macular degeneration.

Authors:  Angela Armento; Marius Ueffing; Simon J Clark
Journal:  Cell Mol Life Sci       Date:  2021-03-09       Impact factor: 9.261

Review 2.  The eye as a complement dysregulation hotspot.

Authors:  Simon J Clark; Paul N Bishop
Journal:  Semin Immunopathol       Date:  2017-09-25       Impact factor: 9.623

3.  Bruch's Membrane Compartmentalizes Complement Regulation in the Eye with Implications for Therapeutic Design in Age-Related Macular Degeneration.

Authors:  Simon J Clark; Selina McHarg; Viranga Tilakaratna; Nicole Brace; Paul N Bishop
Journal:  Front Immunol       Date:  2017-12-19       Impact factor: 7.561

  3 in total

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