| Literature DB >> 21866925 |
Guoqing Wei1, Justin M Chalker, Theodore Cohen.
Abstract
A highly practical synthesis of enantiopure (-)-α-kainic acid is accomplished in 37% overall yield, using 13 linear steps and a minimum of chromatographic separations via an unprecedented TMSCl-promoted palladium-catalyzed zinc-ene cyclization of an allyl acetate.Entities:
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Year: 2011 PMID： 21866925 DOI： 10.1021/jo201341q
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354