| Literature DB >> 21866900 |
Wenbing Ding1, Fanli Zeng, Liangxiong Xu, Yunyun Chen, Yifei Wang, Xiaoyi Wei.
Abstract
Four new dammarane-type saponins, operculinosides A-D (1-4), were isolated from the aerial parts of Operculina turpethum, of which 1 and 2 are the first two dammarane-type triterpenoids having an oxymethyl group at C-24. Their structures were determined by spectroscopic analysis and acid hydrolysis. The absolute configuration of operculinoside A (1) was confirmed by X-ray crystallography. Compounds 1 and 3 showed significant protective activities against d-galactosamine-induced toxicity in L-02 human hepatic cells.Entities:
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Year: 2011 PMID： 21866900 DOI： 10.1021/np200274m
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050