Literature DB >> 21866700

[Active ingredients and efficacies of Ganoderma lucidum cultivated on non-medicinal parts of Chinese medicinal herbs].

Yaohui Guo1, Xia Luo, Mengyao Yu, Linyong Zheng.   

Abstract

OBJECTIVE: Ganoderma lucidum was cultivated on non-medicinal parts of Salvia miltiorrhiza, Chrysanthemum morifolium, Ptatycodgn grandlfiorum, as all are Chinese traditional herbal medicines. We studied the changes of active ingredients and efficacies of the Ganoderma lucidum fruit bodies.
METHODS: The agronomic characters, polysaccharide and terpene contents, acute toxicity and efficacy of Ganoderma lucidum grown on the non-medicinal part of the three materials were compared with that grown on the ordinary formula group (OF. G) which was composed of corn cob, cotton seed shell.
RESULTS: Biological conversion efficiencies of the Ganoderma lucidum fruit body using non-medicinal parts were higher than that of using the ordinary formula group (OF. G), though growth periods became longer; Contents of active ingredients were all improved except that the terpene content of the Salvia miltiorrhiza group was decreased. Both polysaccharide and terpene from the Chrysanthemum morifolium group were the highest, contents of which were respectively 2.47% and 0.79%; Acute toxicity test showed that Ganoderma lucidum fruit bodies were all with low toxicities. Mice maximum tolerance dose were 100 g/kg weight. In hemolysin test and sleeping promotion test, the Chrysanthemum morifolium group showed better effect than the ordinary formula group (OF. G). In anti-fatigue test, only the ordinary formula group (OF. G) proved to be more effective.
CONCLUSION: It's feasible to cultivate Ganoderma lucidum and active ingredients and efficacies of Ganoderma lucidum have been changed using the non-medicinal parts of Chinese medicinal herbs.

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Year:  2011        PMID: 21866700

Source DB:  PubMed          Journal:  Wei Sheng Wu Xue Bao        ISSN: 0001-6209


  1 in total

1.  Total triterpenoids from Ganoderma Lucidum suppresses prostate cancer cell growth by inducing growth arrest and apoptosis.

Authors:  Tao Wang; Zi-Ping Xie; Zhan-Sen Huang; Hao Li; An-Yang Wei; Jin-Ming Di; Heng-Jun Xiao; Zhi-Gang Zhang; Liu-Hong Cai; Xin Tao; Tao Qi; Di-Ling Chen; Jun Chen
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2015-10-22
  1 in total

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