| Literature DB >> 21865416 |
Stuart D Blacksell1, Ampai Tanganuchitcharnchai, Richard G Jarman, Robert V Gibbons, Daniel H Paris, Mark S Bailey, Nicholas P J Day, Ranjan Premaratna, David G Lalloo, H Janaka de Silva.
Abstract
A Sri Lankan fever cohort (n = 292 patients; 17.8% prevalence) was used to assess two standard diagnostic Chikungunya IgM tests. The immunochromatographic test (ICT) acute sample sensitivity (SN) was 1.9 to 3.9%, and specificity (SP) was 92.5 to 95.0%. The enzyme-linked immunosorbent assay (ELISA) gave an acute sample SN of 3.9% and an SP of 92.5% and a convalescent sample SN of 84% and an SP of 91%. These assays are not suitable for the acute diagnosis of Chikungunya virus infection.Entities:
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Year: 2011 PMID: 21865416 PMCID: PMC3187043 DOI: 10.1128/CVI.05288-11
Source DB: PubMed Journal: Clin Vaccine Immunol ISSN: 1556-679X