Literature DB >> 21864824

A systematic review of severe morbidity in infants born late preterm.

Margreet J Teune1, Sabine Bakhuizen, Cynthia Gyamfi Bannerman, Brent C Opmeer, Anton H van Kaam, Aleid G van Wassenaer, Jonathan M Morris, Ben Willen J Mol.   

Abstract

OBJECTIVE: Late-preterm infants (34 weeks 0/7 days-36 weeks 6/7 days' gestation) represent the largest proportion of singleton preterm births. A systematic review was performed to access the short- and/or long-term morbidity of late-preterm infants. STUDY
DESIGN: An electronic search was conducted for cohort studies published from January 2000 through July 2010.
RESULTS: We identified 22 studies studying 29,375,675 infants. Compared with infants born at term, infants born late preterm were more likely to suffer poorer short-term outcomes such as respiratory distress syndrome (relative risk [RR], 17.3), intraventricular hemorrhage (RR, 4.9), and death <28 days (RR, 5.9). Beyond the neonatal period, late-preterm infants were more likely to die in the first year (RR, 3.7) and to suffer from cerebral palsy (RR, 3.1).
CONCLUSION: Although the absolute incidence of neonatal mortality and morbidity in infants born late preterm is low, its incidence is significantly increased as compared with infants born at term.
Copyright © 2011 Mosby, Inc. All rights reserved.

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Year:  2011        PMID: 21864824     DOI: 10.1016/j.ajog.2011.07.015

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  58 in total

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