| Literature DB >> 21863375 |
Alfonso Martín-Fontecha1, Graham M Lord, Hugh J M Brady.
Abstract
Gene expression can be modulated depending on physiological and developmental requirements. A multitude of regulatory genes, which are organized in interdependent networks, guide development and eventually generate specific phenotypes. Transcription factors (TF) are a key element in the regulatory cascade controlling cell fate and effector functions. In this review, we discuss recent data on the diversity of TF that determine natural killer (NK) cell fate and NK cell function.Mesh:
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Year: 2011 PMID: 21863375 DOI: 10.1007/s00018-011-0800-9
Source DB: PubMed Journal: Cell Mol Life Sci ISSN: 1420-682X Impact factor: 9.261