PURPOSE: The aim of our study was to determine the relationship between vision-related quality of life (VRQOL) following the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25) and the macular sensitivity determined by microperimetry in patients with retinitis pigmentosa (RP). METHODS: The Japanese version of the NEI VFQ-25 was used to assess the VRQOL of 30 patients with typical RP whose decimal visual acuity was ≥0.6. The mean retinal sensitivity within the central 10° was determined by fundus-related microperimetry (MP1). The correlation between the mean of the total composite NEI VFQ-25 score and MP1-determined macular sensitivity was determined. RESULTS: Mean NEI VFQ-25 score was 69.4 ± 14.5 (range 34.6-90.3) in RP patients. There was a significant positive correlation between mean NEI VFQ-25 score and mean retinal sensitivity within 10° (r = 0.673, P = 0.0003). CONCLUSION: The significant correlation between macular sensitivity and VRQOL measured with the NEI VFQ-25 indicates that sensitivity in the macular area is an important consideration in using VRQOL with RP patients.
PURPOSE: The aim of our study was to determine the relationship between vision-related quality of life (VRQOL) following the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25) and the macular sensitivity determined by microperimetry in patients with retinitis pigmentosa (RP). METHODS: The Japanese version of the NEI VFQ-25 was used to assess the VRQOL of 30 patients with typical RP whose decimal visual acuity was ≥0.6. The mean retinal sensitivity within the central 10° was determined by fundus-related microperimetry (MP1). The correlation between the mean of the total composite NEI VFQ-25 score and MP1-determined macular sensitivity was determined. RESULTS: Mean NEI VFQ-25 score was 69.4 ± 14.5 (range 34.6-90.3) in RP patients. There was a significant positive correlation between mean NEI VFQ-25 score and mean retinal sensitivity within 10° (r = 0.673, P = 0.0003). CONCLUSION: The significant correlation between macular sensitivity and VRQOL measured with the NEI VFQ-25 indicates that sensitivity in the macular area is an important consideration in using VRQOL with RP patients.
Authors: Yoshimi Suzukamo; Tetsuro Oshika; Mitsuko Yuzawa; Yoshihiro Tokuda; Atsuo Tomidokoro; Kotaro Oki; Carol M Mangione; Joseph Green; Shunichi Fukuhara Journal: Health Qual Life Outcomes Date: 2005-10-26 Impact factor: 3.186
Authors: Rubens C Siqueira; Andre Messias; Katharina Messias; Rafael S Arcieri; Milton A Ruiz; Neiglene F Souza; Lia C Martins; Rodrigo Jorge Journal: Stem Cell Res Ther Date: 2015-03-14 Impact factor: 6.832
Authors: Marta P Wiącek; Wojciech Gosławski; Aleksandra Grabowicz; Anna Sobuś; Miłosz P Kawa; Bartłomiej Baumert; Edyta Paczkowska; Sławomir Milczarek; Bogumiła Osękowska; Krzysztof Safranow; Alicja Zawiślak; Wojciech Lubiński; Bogusław Machaliński; Anna Machalińska Journal: Stem Cells Int Date: 2021-06-02 Impact factor: 5.443