Literature DB >> 21861724

The potential of fenugreek (Trigonella foenum-graecum) as a functional food and nutraceutical and its effects on glycemia and lipidemia.

Keisha T Roberts1.   

Abstract

Dietary fiber from fenugreek blunts glucose and cholesterol after a meal and regulates the production of cholesterol in the liver. The mechanisms for these effects have not been fully elucidated. Fenugreek seeds contain 45.4% dietary fiber (32% insoluble and 13.3% soluble), and the gum is composed of galactose and mannose. The latter compounds are associated with reduced glycemia and cholesterolemia. Fenugreek's hypoglycemic effect has been especially documented in humans and animals with type 1 and type 2 diabetes mellitus. In addition, this dietary fiber has potential for widespread use in the food industry because its galactomannan composition has emulsifying and stabilizing properties. Flour supplemented with 8%-10% fenugreek dietary fiber has been used in the production of baked goods such as bread, pizza, muffins, and cakes. This application to flour allows for the production of functional foods that may be widely acceptable to consumers observing western diets.

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Year:  2011        PMID: 21861724     DOI: 10.1089/jmf.2011.0002

Source DB:  PubMed          Journal:  J Med Food        ISSN: 1096-620X            Impact factor:   2.786


  21 in total

Review 1.  Complementary, holistic, and integrative medicine: advice for clinicians on herbs and breastfeeding.

Authors:  Katarzyna Budzynska; Zoë E Gardner; Tieraona Low Dog; Paula Gardiner
Journal:  Pediatr Rev       Date:  2013-08

2.  Preclinical safety evaluation of low molecular weight galactomannans based standardized fenugreek seeds extract.

Authors:  Pallavi Deshpande; Vishwaraman Mohan; Prasad Thakurdesai
Journal:  EXCLI J       Date:  2016-07-13       Impact factor: 4.068

Review 3.  Diosgenin, 4-hydroxyisoleucine, and fiber from fenugreek: mechanisms of actions and potential effects on metabolic syndrome.

Authors:  Scott Fuller; Jacqueline M Stephens
Journal:  Adv Nutr       Date:  2015-03-13       Impact factor: 8.701

4.  Isolation of Positive Modulator of Glucagon-like Peptide-1 Signaling from Trigonella foenum-graecum (Fenugreek) Seed.

Authors:  Klim King; Nai-Pin Lin; Yu-Hong Cheng; Gao-Hui Chen; Rong-Jie Chein
Journal:  J Biol Chem       Date:  2015-09-02       Impact factor: 5.157

5.  The identification of a novel SIRT6 modulator from Trigonella foenum-graecum using ligand fishing with protein coated magnetic beads.

Authors:  N Singh; S Ravichandran; K Spelman; S D Fugmann; R Moaddel
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2014-03-15       Impact factor: 3.205

6.  Role of Fenugreek in the prevention of type 2 diabetes mellitus in prediabetes.

Authors:  Arpana Gaddam; Chandrakala Galla; Sreenivas Thummisetti; Ravi Kumar Marikanty; Uma D Palanisamy; Paturi V Rao
Journal:  J Diabetes Metab Disord       Date:  2015-10-02

7.  A multicenter clinical study to determine the efficacy of a novel fenugreek seed (Trigonella foenum-graecum) extract (Fenfuro™) in patients with type 2 diabetes.

Authors:  Narsingh Verma; Kauser Usman; Naresh Patel; Arvind Jain; Sudhir Dhakre; Anand Swaroop; Manashi Bagchi; Pawan Kumar; Harry G Preuss; Debasis Bagchi
Journal:  Food Nutr Res       Date:  2016-10-11       Impact factor: 3.894

8.  Preclinical Toxicological Evaluation of IDM01: The Botanical Composition of 4-Hydroxyisoleucine- and Trigonelline-based Standardized Fenugreek Seed Extract.

Authors:  Pallavi O Deshpande; Vishwaraman Mohan; Prasad Arvind Thakurdesai
Journal:  Pharmacognosy Res       Date:  2017 Apr-Jun

Review 9.  Traditional Indian medicines used for the management of diabetes mellitus.

Authors:  Syed Ibrahim Rizvi; Neetu Mishra
Journal:  J Diabetes Res       Date:  2013-06-05       Impact factor: 4.011

10.  Fenugreek Prevents the Development of STZ-Induced Diabetic Nephropathy in a Rat Model of Diabetes.

Authors:  Yingli Jin; Yan Shi; Yinggang Zou; Chunsheng Miao; Bo Sun; Cai Li
Journal:  Evid Based Complement Alternat Med       Date:  2014-05-08       Impact factor: 2.629

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