BACKGROUND: To correlate the three-dimensional (3D) spectral-domain optical coherence tomography (SD-OCT) features of retinal-choroidal anastomosis (RCA) to conventional angiography. METHODS: This is a retrospective chart review of consecutive patients diagnosed with RCA who underwent 3D SD-OCT between July 2007 and June 2010. Main outcome measures were the diagnostic capabilities of 3D SD-OCT, and the correlation between 3D findings and the features distinguished by conventional angiography. RESULTS: Eighteen eyes of 18 patients [five males, 13 females, mean age 79.5 ± 19.4 years (range, 70-93 years)] were included in the analysis. In eyes (n = 3) showing a focal staining on angiography, 3D OCT revealed a slight convex prominence of the inner retinal surface in correspondence of a small dome-shaped retinal pigment epithelium (RPE) elevation (which represented the early RCA). In eyes (n = 7) showing a "hot spot" without pigment epithelium detachment (PED) on angiography, 3D OCT revealed a convex prominence of the inner retinal surface in correspondence with a well-demarcated prominence of RPE with steep margins (which represented the RCA). In eyes (n = 8) showing a "hot spot" with PED on angiography, 3D OCT revealed a convex prominence of the inner retinal surface in correspondence with a convex RPE prominence with a peak at the top. CONCLUSIONS: 3D SD-OCT provides a map of the retina and RPE, allowing a realistic visualization of the different pathological features in the disease development, and may be able to provide clinically relevant information to complement angiography in the diagnosis of RCA.
BACKGROUND: To correlate the three-dimensional (3D) spectral-domain optical coherence tomography (SD-OCT) features of retinal-choroidal anastomosis (RCA) to conventional angiography. METHODS: This is a retrospective chart review of consecutive patients diagnosed with RCA who underwent 3D SD-OCT between July 2007 and June 2010. Main outcome measures were the diagnostic capabilities of 3D SD-OCT, and the correlation between 3D findings and the features distinguished by conventional angiography. RESULTS: Eighteen eyes of 18 patients [five males, 13 females, mean age 79.5 ± 19.4 years (range, 70-93 years)] were included in the analysis. In eyes (n = 3) showing a focal staining on angiography, 3D OCT revealed a slight convex prominence of the inner retinal surface in correspondence of a small dome-shaped retinal pigment epithelium (RPE) elevation (which represented the early RCA). In eyes (n = 7) showing a "hot spot" without pigment epithelium detachment (PED) on angiography, 3D OCT revealed a convex prominence of the inner retinal surface in correspondence with a well-demarcated prominence of RPE with steep margins (which represented the RCA). In eyes (n = 8) showing a "hot spot" with PED on angiography, 3D OCT revealed a convex prominence of the inner retinal surface in correspondence with a convex RPE prominence with a peak at the top. CONCLUSIONS: 3D SD-OCT provides a map of the retina and RPE, allowing a realistic visualization of the different pathological features in the disease development, and may be able to provide clinically relevant information to complement angiography in the diagnosis of RCA.
Authors: Susanna S Park; Steven N Truong; Robert J Zawadzki; Suhail Alam; Stacey S Choi; David G Telander; John S Werner; Lawrence S Morse Journal: Invest Ophthalmol Vis Sci Date: 2010-03-10 Impact factor: 4.799
Authors: J S Slakter; L A Yannuzzi; U Schneider; J A Sorenson; A Ciardella; D R Guyer; R F Spaide; K B Freund; D A Orlock Journal: Ophthalmology Date: 2000-04 Impact factor: 12.079
Authors: Panagiotis Malamos; Stefan Sacu; Michael Georgopoulos; Christopher Kiss; Christian Pruente; Ursula Schmidt-Erfurth Journal: Invest Ophthalmol Vis Sci Date: 2009-06-03 Impact factor: 4.799
Authors: Antonio García-Ben; Radua Kamal-Salah; Ignacio García-Basterra; Ana Gonzalez Gómez; María José Morillo Sanchez; Jose Manuel García-Campos Journal: Graefes Arch Clin Exp Ophthalmol Date: 2017-01-17 Impact factor: 3.117
Authors: Nicole El-Darzi; Natalia Mast; David A Buchner; Aicha Saadane; Brian Dailey; Georgios Trichonas; Irina A Pikuleva Journal: Front Pharmacol Date: 2022-06-01 Impact factor: 5.988