Shaohua Ma1, Yu Sun, Changzheng Du, Zhen Liang, Hongchao Xiong, Keneng Chen. 1. Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Thoracic Surgery I, Peking University School of Oncology, Beijing Cancer Hospital and Institute, Beijing 100142, China.
Abstract
BACKGROUND: The concept of pulmonary sclerosing hemangioma (PSH) was proposed only 50 years ago. PSH features several characteristics that should be differently diagnosed with lung cancer. The aim of this study is to retrospectively review the diagnosis and treatment of 48 cases of PSH, review recent publications about this topic, and address reasonable diagnosis and treatment methods. METHODS: Forty-eight patients with PSH were enrolled and consecutively treated from January 2001 to April 2011. Clinical presentations, image characteristics, pathologic morphologies, and prognostic data were analyzed. RESULTS: Twenty-seven PSH cases (56.3%) were asymptomatic. Tumor diameters ranged from 0.2 to 7.0 cm, with an average diameter of 2.1 cm, and involved both lobes of the lungs. Enlarged lymph nodes in the mediastinum were detected via computed tomography (CT) scans in 15 cases (31.3%). Only 47 patients underwent surgery. Pulmonary wedge resection was performed in 29 cases (61.7%) while lobectomy was performed in 14 (29.8%). The tumor was removed in 3 cases (6.4%) and anterior mediastinal tumor resection was performed in 1 case (2.1%). Forty-seven patients reported no recurrence during follow-up while one patient refused surgery after a CT-guided biopsy with no progression during the 28-month follow up period. CONCLUSIONS: The exact diagnosis of PSH is difficult prior to surgery. Surgery is an effective method of treatment that allows both definite diagnosis and accurate therapy. The prognosis of PSH is favorable.
BACKGROUND: The concept of pulmonary sclerosing hemangioma (PSH) was proposed only 50 years ago. PSH features several characteristics that should be differently diagnosed with lung cancer. The aim of this study is to retrospectively review the diagnosis and treatment of 48 cases of PSH, review recent publications about this topic, and address reasonable diagnosis and treatment methods. METHODS: Forty-eight patients with PSH were enrolled and consecutively treated from January 2001 to April 2011. Clinical presentations, image characteristics, pathologic morphologies, and prognostic data were analyzed. RESULTS: Twenty-seven PSH cases (56.3%) were asymptomatic. Tumor diameters ranged from 0.2 to 7.0 cm, with an average diameter of 2.1 cm, and involved both lobes of the lungs. Enlarged lymph nodes in the mediastinum were detected via computed tomography (CT) scans in 15 cases (31.3%). Only 47 patients underwent surgery. Pulmonary wedge resection was performed in 29 cases (61.7%) while lobectomy was performed in 14 (29.8%). The tumor was removed in 3 cases (6.4%) and anterior mediastinal tumor resection was performed in 1 case (2.1%). Forty-seven patients reported no recurrence during follow-up while one patient refused surgery after a CT-guided biopsy with no progression during the 28-month follow up period. CONCLUSIONS: The exact diagnosis of PSH is difficult prior to surgery. Surgery is an effective method of treatment that allows both definite diagnosis and accurate therapy. The prognosis of PSH is favorable.
Authors: Jeremy Neuman; Alex Rosioreanu; Allan Schuss; George Turi; Elizabeth Yung; Terence K Trow; Lewis Williams; Douglas S Katz Journal: Clin Imaging Date: 2006 Nov-Dec Impact factor: 1.605
Authors: Myung Jin Chung; Kyung Soo Lee; Joungho Han; Yon Mi Sung; Semin Chong; O Jung Kwon Journal: AJR Am J Roentgenol Date: 2006-08 Impact factor: 3.959