Ti/Pd-promoted intramolecular Michael-type addition of allylic carboxylates to activated alkenes.

An interesting protocol for the synthesis of different vinyl substituted carbo- and heterocycles based on a new intramolecular Michael-type reaction using allylic carboxylates as pronucleophiles is reported. The success of the catalytic process is based on the excellent cooperation between the late transition metal (palladium) and the radical reagent (titanium). This journal is © The Royal Society of Chemistry 2011