Literature DB >> 21858317

Spirocyclic systems derived from pyroglutamic acid.

Andrew R Cowley1, Thomas J Hill, Petr Kocis, Mark G Moloney, Robert D Stevenson, Amber L Thompson.   

Abstract

The synthesis and likely conformational structure of rigid spirocyclic bislactams and lactam-lactones derived from pyroglutamic acid, and their suitability as lead structures for applications in drug development programmes using cheminformatic analysis, has been investgated.

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Year:  2011        PMID： 21858317     DOI： 10.1039/c1ob05708a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  4 in total

1.  Functionalised bicyclic tetramates derived from cysteine as antibacterial agents.

Authors:  Tharindi D Panduwawala; Sarosh Iqbal; Amber L Thompson; Miroslav Genov; Alexander Pretsch; Dagmar Pretsch; Shuang Liu; Richard H Ebright; Alison Howells; Anthony Maxwell; Mark G Moloney
Journal:  Org Biomol Chem       Date:  2019-06-05       Impact factor: 3.876

Review 2.  Acyclic Twisted Amides.

Authors:  Guangrong Meng; Jin Zhang; Michal Szostak
Journal:  Chem Rev       Date:  2021-08-18       Impact factor: 72.087

3.  Lithium Enolates Derived from Pyroglutaminol: Mechanism and Stereoselectivity of an Azaaldol Addition.

Authors:  Michael J Houghton; Christopher J Huck; Stephen W Wright; David B Collum
Journal:  J Am Chem Soc       Date:  2016-08-08       Impact factor: 15.419

4.  Lithium Enolates Derived from Pyroglutaminol: Aggregation, Solvation, and Atropisomerism.

Authors:  Michael J Houghton; Naomi A Biok; Christopher J Huck; Russell F Algera; Ivan Keresztes; Stephen W Wright; David B Collum
Journal:  J Org Chem       Date:  2016-04-25       Impact factor: 4.354
  4 in total

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