OBJECTIVE: To determine the causes and characteristics of maternal deaths in HIV-infected women. DESIGN: A retrospective study of maternal deaths in a cohort of HIV-infected women. SETTING: A facility-based maternal death review using case records and mortality summaries. METHODS: Thirty seven maternal deaths which occurred in HIV-infected women were reviewed in a university teaching hospital in southern Nigeria over a 4-year period. Causes and circumstances surrounding each maternal death were identified. RESULT: One in every four maternal deaths occur in women with HIV infection. Majority (64.9%) of the women presented in advanced stage (WHO stage III/IV) of HIV syndrome while 86.5% had missed opportunities for antiretroviral programme. Pregnancy-related sepsis was the commonest cause of maternal death. Other common causes were death from tuberculosis and pneumonia. CONCLUSION: HIV-related maternal death is emerging as a leading cause of pregnancy related death in Nigeria. There is need to scale-up preconception care and ensure comprehensive and sustainable prevention of mother -to-child transmission service for all pregnant women throughout Nigeria to reduce the burden of HIV/AIDS infection and minimize avoidable deaths from opportunistic infections.
OBJECTIVE: To determine the causes and characteristics of maternal deaths in HIV-infectedwomen. DESIGN: A retrospective study of maternal deaths in a cohort of HIV-infectedwomen. SETTING: A facility-based maternal death review using case records and mortality summaries. METHODS: Thirty seven maternal deaths which occurred in HIV-infectedwomen were reviewed in a university teaching hospital in southern Nigeria over a 4-year period. Causes and circumstances surrounding each maternal death were identified. RESULT: One in every four maternal deaths occur in women with HIV infection. Majority (64.9%) of the women presented in advanced stage (WHO stage III/IV) of HIV syndrome while 86.5% had missed opportunities for antiretroviral programme. Pregnancy-related sepsis was the commonest cause of maternal death. Other common causes were death from tuberculosis and pneumonia. CONCLUSION: HIV-related maternal death is emerging as a leading cause of pregnancy related death in Nigeria. There is need to scale-up preconception care and ensure comprehensive and sustainable prevention of mother -to-child transmission service for all pregnant women throughout Nigeria to reduce the burden of HIV/AIDS infection and minimize avoidable deaths from opportunistic infections.
Entities:
Keywords:
AIDS; Antiretroviral therapy; HIV Infection; Maternal Death; Nigeria
Authors: Abubakar Ali Kullima; Mohammed Bello Kawuwa; Bala Mohammed Audu; Ado Danazumi Geidam; Abdulkarim G Mairiga Journal: Ann Afr Med Date: 2009 Oct-Dec
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Authors: Tamil Kendall; Isabella Danel; Diane Cooper; Sophie Dilmitis; Angela Kaida; Athena P Kourtis; Ana Langer; Ilana Lapidos-Salaiz; Eva Lathrop; Allisyn C Moran; Hannah Sebitloane; Janet M Turan; D Heather Watts; Mary Nell Wegner Journal: J Acquir Immune Defic Syndr Date: 2014-12-01 Impact factor: 3.731