Literature DB >> 21856572

Causes for treatment delays in dystonia and hemifacial spasm: a Canadian survey.

Mandar Jog1, Sylvain Chouinard, Doug Hobson, David Grimes, Robert Chen, Meetu Bhogal, Susan Simonyi.   

Abstract

BACKGROUND: Dystonia must be accurately diagnosed so that treatment can be administered promptly. However, dystonia is a complex disorder, with variable presentation, which can delay diagnosis.
METHODS: Data were gathered by questionnaire from 866 patients with dystonia or hemifacial spasm (HFS) treated in 14 movement disorders centres in Canada injecting botulinum toxin, to better understand the path to diagnosis, wait times and obstacles to treatment.
RESULTS: Most participants were female (64.1%), mean age was 58 years, and patients consulted an average of 3.2 physicians before receiving a dystonia or HFS diagnosis. Many patients (34%) received other diagnoses before referral to a movement disorders clinic, most commonly "stress" (42.7%). A variety of treatments were often received without a diagnosis. The mean lag time between symptom onset and diagnosis was 5.4 years. After the decision to use botulinum toxin, patients waited a mean of 3.1 months before treatment. The most common diagnoses were cervical dystonia (51.6% of patients), HFS (20.0%) and blepharospasm (9.8%).
CONCLUSIONS: Survey results show that diagnosis of dystonias or of HFS, and therefore, access to treatment, is delayed. An educational program for primary care physicians may be helpful to decrease the time to diagnosis and referral to a specialist centre for treatment.

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Year:  2011        PMID: 21856572     DOI: 10.1017/s0317167100012270

Source DB:  PubMed          Journal:  Can J Neurol Sci        ISSN: 0317-1671            Impact factor:   2.104


  13 in total

Review 1.  Diagnosis and treatment of dystonia.

Authors:  H A Jinnah; Stewart A Factor
Journal:  Neurol Clin       Date:  2015-02       Impact factor: 3.806

2.  Evaluation of anxiety and depression scales and quality of LIFE in cervical dystonia patients on botulinum toxin therapy and their relatives.

Authors:  Dursun Ceylan; Sevda Erer; Mehmet Zarifoğlu; Nevin Türkeş; Güven Özkaya
Journal:  Neurol Sci       Date:  2019-01-18       Impact factor: 3.307

Review 3.  Deep brain stimulation for dystonia: a novel perspective on the value of genetic testing.

Authors:  H A Jinnah; Ron Alterman; Christine Klein; Joachim K Krauss; Elena Moro; Marie Vidailhet; Robert Raike
Journal:  J Neural Transm (Vienna)       Date:  2017-02-03       Impact factor: 3.575

Review 4.  Recent developments in dystonia.

Authors:  Hyder A Jinnah; Jan K Teller; Wendy R Galpern
Journal:  Curr Opin Neurol       Date:  2015-08       Impact factor: 5.710

5.  Diagnostic Process in Rare Diseases: Determinants Associated with Diagnostic Delay.

Authors:  Juan Benito-Lozano; Greta Arias-Merino; Mario Gómez-Martínez; Alba Ancochea-Díaz; Aitor Aparicio-García; Manuel Posada de la Paz; Verónica Alonso-Ferreira
Journal:  Int J Environ Res Public Health       Date:  2022-05-26       Impact factor: 4.614

6.  Development and validation of a clinical guideline for diagnosing blepharospasm.

Authors:  Giovanni Defazio; Mark Hallett; Hyder A Jinnah; Alfredo Berardelli
Journal:  Neurology       Date:  2013-06-14       Impact factor: 9.910

Review 7.  The focal dystonias: current views and challenges for future research.

Authors:  H A Jinnah; Alfredo Berardelli; Cynthia Comella; Giovanni Defazio; Mahlon R Delong; Stewart Factor; Wendy R Galpern; Mark Hallett; Christy L Ludlow; Joel S Perlmutter; Ami R Rosen
Journal:  Mov Disord       Date:  2013-06-15       Impact factor: 10.338

8.  How long does it take to diagnose cervical dystonia?

Authors:  Evan Tiderington; Emily M Goodman; Ami R Rosen; Edie R Hapner; Michael M Johns; Marian L Evatt; Alan Freeman; Stewart Factor; H A Jinnah
Journal:  J Neurol Sci       Date:  2013-08-30       Impact factor: 3.181

9.  Descriptive epidemiology of cervical dystonia.

Authors:  Giovanni Defazio; Joseph Jankovic; Jennifer L Giel; Spyridon Papapetropoulos
Journal:  Tremor Other Hyperkinet Mov (N Y)       Date:  2013-11-04

10.  Botulinum toxin clinic-based epidemiologic survey of adults with primary dystonia in East china.

Authors:  Li Wang; Xingyue Hu; Chunfeng Liu; Yiwen Wu; Changqing Wang; Zhiqiang Wang; Jun Chen
Journal:  J Mov Disord       Date:  2012-05-30
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