Literature DB >> 21856183

Appendectomy during pregnancy: follow-up of progeny.

Jacqueline J Choi1, Rose Mustafa, Elizabeth T Lynn, Celia M Divino.   

Abstract

BACKGROUND: The incidence of appendicitis in pregnant patients is 0.04% to 0.20%, making it the most common nonobstetric surgical procedure in pregnancy. This study examines whether an appendectomy during any stage of pregnancy affects future development of motor, sensory, and social skills of the progeny. STUDY
DESIGN: A prospective survey was administered to women who underwent an appendectomy during pregnancy at Mount Sinai Hospital from 2000 to 2009. The survey, which ranged from 1 to 9 years postpartum, consisted of questions about motor, sensory, and social development of their progeny, based on established pediatric milestones. Data were collected from the medical records of mother and child. Additional follow-up was gathered from outpatient and emergency room records.
RESULTS: Fifty-two pregnant patients underwent an appendectomy during our study period. All pregnancies continued to full term with the exception of one fetal death due to extreme prematurity. Twenty-nine patients completed the follow-up survey, making the yield response rate 55.8%. There were 7 (26.9%), 14 (48.3%), and 8 (27.6%) appendectomies in the first, second, and third trimesters, respectively. Mean follow-up time was 47.2 months (range 13 to 117 months) after delivery. None of the children exhibited any developmental delay by their third year of life. Timing of the surgery (trimester) had no effect on child development.
CONCLUSIONS: Appendectomy during pregnancy is not associated with developmental delays in children, regardless of which trimester the procedure was performed. All children in this study had normal motor, sensory, and social development by 3 years of age.
Copyright © 2011 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 21856183     DOI: 10.1016/j.jamcollsurg.2011.07.016

Source DB:  PubMed          Journal:  J Am Coll Surg        ISSN: 1072-7515            Impact factor:   6.113


  6 in total

1.  Laparoscopic appendectomy and cholecystectomy versus open: a study in 1999 pregnant patients.

Authors:  T C Cox; C R Huntington; L J Blair; T Prasad; A E Lincourt; V A Augenstein; B T Heniford
Journal:  Surg Endosc       Date:  2015-06-20       Impact factor: 4.584

2.  Meckel's Diverticulum: The "Great Mimic" but Often a Forgotten Cause of Acute Abdomen during Pregnancy.

Authors:  Beatriz Féria; Madalena Trindade; Maria João Palma; Joana Figueiredo; Filipa Passos
Journal:  Case Rep Obstet Gynecol       Date:  2022-06-07

3.  Maternal Exposure of Rats to Isoflurane during Late Pregnancy Impairs Spatial Learning and Memory in the Offspring by Up-Regulating the Expression of Histone Deacetylase 2.

Authors:  Foquan Luo; Yan Hu; Weilu Zhao; Zhiyi Zuo; Qi Yu; Zhiyi Liu; Jiamei Lin; Yunlin Feng; Binda Li; Liuqin Wu; Lin Xu
Journal:  PLoS One       Date:  2016-08-18       Impact factor: 3.240

4.  Pregnancy outcomes following nonobstetric surgery during gestation: a nationwide population-based case-control study in Taiwan.

Authors:  Chia-Hung Yu; Shih-Feng Weng; Chung-Han Ho; Yi-Chen Chen; Jen-Yin Chen; Ying-Jen Chang; Jhi-Joung Wang; Ming-Ping Wu; Chin-Chen Chu
Journal:  BMC Pregnancy Childbirth       Date:  2018-11-26       Impact factor: 3.007

5.  Medical management of appendicitis in early-term pregnancy.

Authors:  Amin Tavakoli; Paul Wadensweiler; Elizabeth Blumenthal; Eric Kuncir; Roozbeh Houshyar; Taylor Brueseke
Journal:  BMJ Case Rep       Date:  2020-08-25

6.  Propofol exposure during late stages of pregnancy impairs learning and memory in rat offspring via the BDNF-TrkB signalling pathway.

Authors:  Liang Zhong; Foquan Luo; Weilu Zhao; Yunlin Feng; Liuqin Wu; Jiamei Lin; Tianyin Liu; Shengqiang Wang; Xuexue You; Wei Zhang
Journal:  J Cell Mol Med       Date:  2016-06-14       Impact factor: 5.310

  6 in total

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