Literature DB >> 21853174

A phosphoarginine containing peptide as an artificial SH2 ligand.

Frank T Hofmann1, Claudia Lindemann, Helen Salia, Philipp Adamitzki, John Karanicolas, Florian P Seebeck.   

Abstract

We have developed a synthesis of phosphoarginine containing peptides using a bis(2,2,2-trichloroethyl) protected phosphoarginine derivative as building block. Binding studies and computer modelling demonstrate the ability of the SH2 domain from Src kinase to recognize a phosphoarginine-containing peptide in a phosphoryl group-dependent manner. This journal is © The Royal Society of Chemistry 2011

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Year:  2011        PMID： 21853174     DOI： 10.1039/c1cc13341a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

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Journal:  Chem Rev       Date:  2014-10-20       Impact factor: 60.622

2.  Synthesis and Use of a Phosphonate Amidine to Generate an Anti-Phosphoarginine-Specific Antibody.

Authors:  Jakob Fuhrmann; Venkataraman Subramanian; Paul R Thompson
Journal:  Angew Chem Int Ed Engl       Date:  2015-10-12       Impact factor: 15.336

3.  Chasing Phosphoarginine Proteins: Development of a Selective Enrichment Method Using a Phosphatase Trap.

Authors:  Débora Broch Trentini; Jakob Fuhrmann; Karl Mechtler; Tim Clausen
Journal:  Mol Cell Proteomics       Date:  2014-05-13       Impact factor: 5.911

4.  Chemoselective synthesis and analysis of naturally occurring phosphorylated cysteine peptides.

Authors:  Jordi Bertran-Vicente; Martin Penkert; Olaia Nieto-Garcia; Jean-Marc Jeckelmann; Peter Schmieder; Eberhard Krause; Christian P R Hackenberger
Journal:  Nat Commun       Date:  2016-09-02       Impact factor: 14.919

5.  Combining free energy calculations with tailored enzyme activity assays to elucidate substrate binding of a phospho-lysine phosphatase.

Authors:  Anett Hauser; Songhwan Hwang; Han Sun; Christian P R Hackenberger
Journal:  Chem Sci       Date:  2020-09-08       Impact factor: 9.825

6.  Evaluation of the interaction between phosphohistidine analogues and phosphotyrosine binding domains.

Authors:  Tom E McAllister; Katherine A Horner; Michael E Webb
Journal:  Chembiochem       Date:  2014-04-25       Impact factor: 3.164
  6 in total

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