Literature DB >> 2185032

DNA methylation in Trypanosoma cruzi.

M V Rojas1, N Galanti.   

Abstract

DNA isolated from the protozoan Trypanosoma cruzi has been found to contain 5-methylcytosine. Analysis of T. cruzi DNA by both HpaII and MspI restriction endonucleases suggests that the sequence -CCGG- is not methylated. Probably T. cruzi DNA also contains N6-methyladenine. This report constitutes the first clear demonstration of the presence of methylated bases in the nuclear DNA from trypanosomes.

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Year:  1990        PMID： 2185032     DOI： 10.1016/0014-5793(90)80717-w

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  4 in total

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  4 in total

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