Literature DB >> 21850098

Stem cells: Orphan receptors find a home.

Walter Birchmeier.   

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Year:  2011        PMID： 21850098     DOI： 10.1038/476287a

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  12 in total

1.  Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.

Authors:  Toshiro Sato; Robert G Vries; Hugo J Snippert; Marc van de Wetering; Nick Barker; Daniel E Stange; Johan H van Es; Arie Abo; Pekka Kujala; Peter J Peters; Hans Clevers
Journal:  Nature       Date:  2009-03-29       Impact factor: 49.962

2.  Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin.

Authors:  Hugo J Snippert; Andrea Haegebarth; Maria Kasper; Viljar Jaks; Johan H van Es; Nick Barker; Marc van de Wetering; Maaike van den Born; Harry Begthel; Robert G Vries; Daniel E Stange; Rune Toftgård; Hans Clevers
Journal:  Science       Date:  2010-03-12       Impact factor: 47.728

3.  Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.

Authors:  Wim de Lau; Nick Barker; Teck Y Low; Bon-Kyoung Koo; Vivian S W Li; Hans Teunissen; Pekka Kujala; Andrea Haegebarth; Peter J Peters; Marc van de Wetering; Daniel E Stange; Johan E van Es; Daniele Guardavaccaro; Richard B M Schasfoort; Yasuaki Mohri; Katsuhiko Nishimori; Shabaz Mohammed; Albert J R Heck; Hans Clevers
Journal:  Nature       Date:  2011-07-04       Impact factor: 49.962

4.  The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia.

Authors:  Diana C Blaydon; Yoshiyuki Ishii; Edel A O'Toole; Harriet C Unsworth; Muy-Teck Teh; Franz Rüschendorf; Claire Sinclair; Väinö K Hopsu-Havu; Nicholas Tidman; Celia Moss; Rosemarie Watson; David de Berker; Muhammad Wajid; Angela M Christiano; David P Kelsell
Journal:  Nat Genet       Date:  2006-10-15       Impact factor: 38.330

5.  R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6.

Authors:  Minke E Binnerts; Kyung-Ah Kim; Jessica M Bright; Sejal M Patel; Karolyn Tran; Mei Zhou; John M Leung; Yi Liu; Woodrow E Lomas; Melissa Dixon; Sophie A Hazell; Marie Wagle; Wen-Sheng Nie; Nenad Tomasevic; Jason Williams; Xiaoming Zhan; Michael D Levy; Walter D Funk; Arie Abo
Journal:  Proc Natl Acad Sci U S A       Date:  2007-09-05       Impact factor: 11.205

6.  An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors.

Authors:  Ittai Ben-Porath; Matthew W Thomson; Vincent J Carey; Ruping Ge; George W Bell; Aviv Regev; Robert A Weinberg
Journal:  Nat Genet       Date:  2008-05       Impact factor: 38.330

7.  The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development.

Authors:  Olga Kazanskaya; Bisei Ohkawara; Melanie Heroult; Wei Wu; Nicole Maltry; Hellmut G Augustin; Christof Niehrs
Journal:  Development       Date:  2008-10-08       Impact factor: 6.868

Review 8.  Wnt signalling and its impact on development and cancer.

Authors:  Alexandra Klaus; Walter Birchmeier
Journal:  Nat Rev Cancer       Date:  2008-05       Impact factor: 60.716

9.  Identification of stem cells in small intestine and colon by marker gene Lgr5.

Authors:  Nick Barker; Johan H van Es; Jeroen Kuipers; Pekka Kujala; Maaike van den Born; Miranda Cozijnsen; Andrea Haegebarth; Jeroen Korving; Harry Begthel; Peter J Peters; Hans Clevers
Journal:  Nature       Date:  2007-10-14       Impact factor: 49.962

10.  R-spondin1 is essential in sex determination, skin differentiation and malignancy.

Authors:  Pietro Parma; Orietta Radi; Valerie Vidal; Marie Christine Chaboissier; Elena Dellambra; Stella Valentini; Liliana Guerra; Andreas Schedl; Giovanna Camerino
Journal:  Nat Genet       Date:  2006-10-15       Impact factor: 38.330
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  16 in total

1.  Ovarian LGR5 is critical for successful pregnancy.

Authors:  Xiaofei Sun; Jumpei Terakawa; Hans Clevers; Nick Barker; Takiko Daikoku; Sudhansu K Dey
Journal:  FASEB J       Date:  2014-01-27       Impact factor: 5.191

2.  Structural basis for R-spondin recognition by LGR4/5/6 receptors.

Authors:  Dongli Wang; Binlu Huang; Senyan Zhang; Xiaojuan Yu; Wei Wu; Xinquan Wang
Journal:  Genes Dev       Date:  2013-06-11       Impact factor: 11.361

3.  Grape exosome-like nanoparticles induce intestinal stem cells and protect mice from DSS-induced colitis.

Authors:  Songwen Ju; Jingyao Mu; Terje Dokland; Xiaoying Zhuang; Qilong Wang; Hong Jiang; Xiaoyu Xiang; Zhong-Bin Deng; Baomei Wang; Lifeng Zhang; Mary Roth; Ruth Welti; James Mobley; Yan Jun; Donald Miller; Huang-Ge Zhang
Journal:  Mol Ther       Date:  2013-06-11       Impact factor: 11.454

4.  R-Spondin 1 promotes vibration-induced bone formation in mouse models of osteoporosis.

Authors:  Haitao Wang; Tracy A Brennan; Elizabeth Russell; Jung-Hoon Kim; Kevin P Egan; Qijun Chen; Craig Israelite; David C Schultz; Frederick B Johnson; Robert J Pignolo
Journal:  J Mol Med (Berl)       Date:  2013-08-24       Impact factor: 4.599

5.  LGR4 and LGR6 are differentially expressed and of putative tumor biological significance in gastric carcinoma.

Authors:  Jan Simon Steffen; Eva Simon; Viktoria Warneke; Katharina Balschun; Matthias Ebert; Christoph Röcken
Journal:  Virchows Arch       Date:  2012-08-02       Impact factor: 4.064

6.  Decreased PTGDS Expression Predicting Poor Survival of Endometrial Cancer by Integrating Weighted Gene Co-Expression Network Analysis and Immunohistochemical Validation.

Authors:  Ruoyao Zou; Mingjun Zheng; Mingzi Tan; Haoya Xu; Nannan Luan; Liancheng Zhu
Journal:  Cancer Manag Res       Date:  2020-06-26       Impact factor: 3.989

Review 7.  Caenorhabditis elegans: A Model System for Anti-Cancer Drug Discovery and Therapeutic Target Identification.

Authors:  Robert A Kobet; Xiaoping Pan; Baohong Zhang; Stephen C Pak; Adam S Asch; Myon-Hee Lee
Journal:  Biomol Ther (Seoul)       Date:  2014-09-30       Impact factor: 4.634

8.  Leucine-rich repeat-containing G-protein-coupled receptor 5 is associated with invasion, metastasis, and could be a potential therapeutic target in human gastric cancer.

Authors:  H Q Xi; A Z Cai; X S Wu; J X Cui; W S Shen; S B Bian; N Wang; J Y Li; C R Lu; Z Song; B Wei; L Chen
Journal:  Br J Cancer       Date:  2014-03-04       Impact factor: 7.640

9.  Comparative expression study of the endo-G protein coupled receptor (GPCR) repertoire in human glioblastoma cancer stem-like cells, U87-MG cells and non malignant cells of neural origin unveils new potential therapeutic targets.

Authors:  Marie Fève; Jean-Michel Saliou; Maria Zeniou; Sarah Lennon; Christine Carapito; Jihu Dong; Alain Van Dorsselaer; Marie-Pierre Junier; Hervé Chneiweiss; Sarah Cianférani; Jacques Haiech; Marie-Claude Kilhoffer
Journal:  PLoS One       Date:  2014-03-24       Impact factor: 3.240

10.  R-spondin 3 regulates dorsoventral and anteroposterior patterning by antagonizing Wnt/β-catenin signaling in zebrafish embryos.

Authors:  Xiaozhi Rong; Chen Chen; Pin Zhou; Yumei Zhou; Yun Li; Ling Lu; Yunzhang Liu; Jianfeng Zhou; Cunming Duan
Journal:  PLoS One       Date:  2014-06-11       Impact factor: 3.240
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