Literature DB >> 2184743

How lymphocytes kill.

L H Young1, C C Liu, S Joag, S Rafii, J D Young.   

Abstract

Cytotoxic T lymphocytes and natural killer cells are potent killers of target cells. These lymphocytes have large cytoplasmic granules containing cytotoxic peptides and other factors. Several of these molecules have been isolated and their functions elucidated. These molecules may be directly involved in the killing of virus-infected and transformed cells as well as in the development of cell-mediated autoimmune disorders.

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Year:  1990        PMID: 2184743     DOI: 10.1146/annurev.me.41.020190.000401

Source DB:  PubMed          Journal:  Annu Rev Med        ISSN: 0066-4219            Impact factor:   13.739


  6 in total

1.  Transplantation of β-endorphin neurons into the hypothalamus promotes immune function and restricts the growth and metastasis of mammary carcinoma.

Authors:  Dipak K Sarkar; Changqing Zhang; Sengottuvelan Murugan; Madhavi Dokur; Nadka I Boyadjieva; Maria Ortigüela; Kenneth R Reuhl; Sepide Mojtehedzadeh
Journal:  Cancer Res       Date:  2011-08-11       Impact factor: 12.701

2.  Lymphocyte activation and serine-esterase induction following recombinant interleukin-2 infusion for lymphomas and acute leukaemias.

Authors:  S H Lim; C Worman; A Jewell; C Tsakona; F J Giles; A Goldstone
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968

3.  Expression of cytolytic mediators by synovial fluid lymphocytes in rheumatoid arthritis.

Authors:  L H Young; S V Joag; P Y Lin; S F Luo; L M Zheng; C C Liu; J D Young
Journal:  Am J Pathol       Date:  1992-05       Impact factor: 4.307

4.  A pore-forming protein, perforin, from a non-mammalian organism, Japanese flounder, Paralichthys olivaceus.

Authors:  Jee Youn Hwang; Tsuyoshi Ohira; Ikuo Hirono; Takashi Aoki
Journal:  Immunogenetics       Date:  2004-07-29       Impact factor: 2.846

5.  Suppression of rat cytomegalovirus replication by antibodies against gamma interferon.

Authors:  B L Haagmans; P H van der Meide; F S Stals; A J van den Eertwegh; E Claassen; C A Bruggeman; M C Horzinek; V E Schijns
Journal:  J Virol       Date:  1994-04       Impact factor: 5.103

6.  Counting CD4(+) and CD8(+) T cells in the spleen: a novel in vivo method for assessing biomaterial immunotoxicity.

Authors:  Shyh-Jou Shieh; Prashanth Varkey; Po-Yang Chen; Su-Ya Chang; Lynn L H Huang
Journal:  Regen Biomater       Date:  2014-10-20
  6 in total

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