Literature DB >> 2184726

Cellular mechanism for ischemic ventricular arrhythmias.

L H Opie1, W T Clusin.   

Abstract

Two of the major ionic abnormalities found early in ischemia are (a) loss of potassium with an increase in the extracellular potassium ion concentration and (b) an increase in free cytosolic calcium. Both of these ionic abnormalities can powerfully predispose to the development of arrhythmias.

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Year:  1990        PMID： 2184726     DOI： 10.1146/annurev.me.41.020190.001311

Source DB:  PubMed          Journal:  Annu Rev Med        ISSN： 0066-4219            Impact factor:   13.739


  14 in total

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Review 3.  Glucose and glycogen utilisation in myocardial ischemia--changes in metabolism and consequences for the myocyte.

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Review 4.  Calcium antagonists post-infarction: the significance of experimental studies on potentially lethal early ischemic ventricular arrhythmias.

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5.  Functional Interactions between Distinct Sodium Channel Cytoplasmic Domains through the Action of Calmodulin.

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Review 9.  Risk stratification after myocardial infarction: role of electrical instability, ischemia, and left ventricular function.

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10.  Cariporide given during resuscitation promotes return of electrically stable and mechanically competent cardiac activity.

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