Literature DB >> 21846175

Drug monitoring of a case of citalopram overdosage.

Jérôme Liotier1, François Coudoré.   

Abstract

Selective serotonin reuptake inhibitors are widely prescribed drugs without recognized cardiovascular risk. We report the case of a 54-year-old patient who developed QTc interval prolongation, followed by ventricular fibrillation episodes, 10 hours after admission to the ICU, in the setting of a citalopram overdose. Citalopram plasma values dropped from 5.88 to 0.34 mg/L at 9 days postadmission. The patient was treated by oral activated charcoal, and final outcome was favorable.

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Year:  2011        PMID: 21846175     DOI: 10.3109/01480545.2011.566571

Source DB:  PubMed          Journal:  Drug Chem Toxicol        ISSN: 0148-0545            Impact factor:   3.356


  6 in total

1.  Real Patient and its Virtual Twin: Application of Quantitative Systems Toxicology Modelling in the Cardiac Safety Assessment of Citalopram.

Authors:  Nikunjkumar Patel; Barbara Wiśniowska; Masoud Jamei; Sebastian Polak
Journal:  AAPS J       Date:  2017-11-27       Impact factor: 4.009

2.  The Effects of the Adenosine Receptor Antagonists on the Reverse of Cardiovascular Toxic Effects Induced by Citalopram In-Vivo Rat Model of Poisoning.

Authors:  Müjgan Büyükdeligöz; Nil Hocaoğlu; Kubilay Oransay; Yeşim Tunçok; Şule Kalkan
Journal:  Balkan Med J       Date:  2015-07-01       Impact factor: 2.021

Review 3.  Citalopram and cardiac toxicity.

Authors:  M J Cooke; W S Waring
Journal:  Eur J Clin Pharmacol       Date:  2012-09-21       Impact factor: 2.953

Review 4.  QTc interval prolongation and torsade de pointes associated with second-generation antipsychotics and antidepressants: a comprehensive review.

Authors:  Mehrul Hasnain; W Victor R Vieweg
Journal:  CNS Drugs       Date:  2014-10       Impact factor: 5.749

5.  Prediction of Ventricular Arrhythmias by QRS/QTc - Ratio in Citalopram or Escitalopram Intoxication.

Authors:  Erik Sveberg Dietrichs; Godfrey L Smith
Journal:  Front Med (Lausanne)       Date:  2022-03-16

6.  The role of adenosine receptors and endogenous adenosine in citalopram-induced cardiovascular toxicity.

Authors:  Kubilay Oransay; Nil Hocaoglu; Mujgan Buyukdeligoz; Yesim Tuncok; Sule Kalkan
Journal:  Indian J Pharmacol       Date:  2014 Jul-Aug       Impact factor: 1.200

  6 in total

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