Literature DB >> 21844325

Functional characterization of Tn4401, a Tn3-based transposon involved in blaKPC gene mobilization.

Gaelle Cuzon1, Thierry Naas, Patrice Nordmann.   

Abstract

The carbapenemase gene bla(KPC), which is rapidly spreading worldwide, is located on a Tn3-based transposon, Tn4401. In a transposition-conjugation assay, Tn4401 was able to mobilize bla(KPC-2) gene at a frequency of 4.4 × 10(-6)/recipient cell. A 5-bp target site duplication was evidenced upon each insertion without target site specificity. This study demonstrated that Tn4401 is an active transposon capable of mobilizing bla(KPC) genes at high frequency.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21844325      PMCID： PMC3195030          DOI： 10.1128/AAC.05202-11

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  26 in total

Review 1.  Playing second fiddle: second-strand processing and liberation of transposable elements from donor DNA.

Authors:  C Turlan; M Chandler
Journal:  Trends Microbiol       Date:  2000-06       Impact factor: 17.079

2.  Dissemination of blaKPC-2 by the spread of Klebsiella pneumoniae clonal complex 258 clones (ST258, ST11, ST437) and plasmids (IncFII, IncN, IncL/M) among Enterobacteriaceae species in Brazil.

Authors:  Leonardo Neves Andrade; Tânia Curiao; Joseane Cristina Ferreira; Juliana Mucedola Longo; Eduardo Carneiro Clímaco; Roberto Martinez; Fernando Bellissimo-Rodrigues; Aníbal Basile-Filho; Marco Antônio Evaristo; Pedro F Del Peloso; Vanessa Bley Ribeiro; Afonso Luis Barth; Milena Cristina Paula; Fernando Baquero; Rafael Cantón; Ana Lúcia da Costa Darini; Teresa M Coque
Journal:  Antimicrob Agents Chemother       Date:  2011-05-16       Impact factor: 5.191

3.  Copy number control of Tn5 transposition.

Authors:  R C Johnson; W S Reznikoff
Journal:  Genetics       Date:  1984-05       Impact factor: 4.562

4.  Molecular characterization of In50, a class 1 integron encoding the gene for the extended-spectrum beta-lactamase VEB-1 in Pseudomonas aeruginosa.

Authors:  T Naas; L Poirel; A Karim; P Nordmann
Journal:  FEMS Microbiol Lett       Date:  1999-07-15       Impact factor: 2.742

5.  Molecular characterization of a novel class 1 integron containing bla(GES-1) and a fused product of aac3-Ib/aac6'-Ib' gene cassettes in Pseudomonas aeruginosa.

Authors:  Véronique Dubois; Laurent Poirel; Caroline Marie; Corinne Arpin; Patrice Nordmann; Claudine Quentin
Journal:  Antimicrob Agents Chemother       Date:  2002-03       Impact factor: 5.191

6.  Factors affecting the isolation of CCC DNA from Streptomyces lividans and Escherichia coli.

Authors:  T Kieser
Journal:  Plasmid       Date:  1984-07       Impact factor: 3.466

7.  CARB-9, a carbenicillinase encoded in the VCR region of Vibrio cholerae non-O1, non-O139 belongs to a family of cassette-encoded beta-lactamases.

Authors:  Alejandro Petroni; Roberto G Melano; Héctor A Saka; Alicia Garutti; Laura Mange; Fernando Pasterán; Melina Rapoport; Mariana Miranda; Diego Faccone; Alicia Rossi; Paul S Hoffman; Marcelo F Galas
Journal:  Antimicrob Agents Chemother       Date:  2004-10       Impact factor: 5.191

8.  Translocation of antibiotic resistance determinants including an extended-spectrum beta-lactamase between conjugative plasmids of Klebsiella pneumoniae and Escherichia coli.

Authors:  D Sirot; C De Champs; C Chanal; R Labia; A Darfeuille-Michaud; R Perroux; J Sirot
Journal:  Antimicrob Agents Chemother       Date:  1991-08       Impact factor: 5.191

9.  Transposition of the gene encoding a TEM-12 extended-spectrum beta-lactamase.

Authors:  J Heritage; P M Hawkey; N Todd; I J Lewis
Journal:  Antimicrob Agents Chemother       Date:  1992-09       Impact factor: 5.191

10.  Imipenem resistance in a Salmonella clinical strain due to plasmid-mediated class A carbapenemase KPC-2.

Authors:  Vivi Miriagou; Leonidas S Tzouvelekis; Shannon Rossiter; Eva Tzelepi; Frederick J Angulo; Jean M Whichard
Journal:  Antimicrob Agents Chemother       Date:  2003-04       Impact factor: 5.191
View more
  78 in total

1.  First report of a clinical, multidrug-resistant Enterobacteriaceae isolate coharboring fosfomycin resistance gene fosA3 and carbapenemase gene blaKPC-2 on the same transposon, Tn1721.

Authors:  Gang Li; Ying Zhang; Dexi Bi; Pinghua Shen; Fuqi Ai; Hong Liu; Yueru Tian; Yiming Ma; Bei Wang; Kumar Rajakumar; Hong-Yu Ou; Xiaofei Jiang
Journal:  Antimicrob Agents Chemother       Date:  2014-11-03       Impact factor: 5.191

2.  Role of ISKpn7 and deletions in blaKPC gene expression.

Authors:  Thierry Naas; Gaelle Cuzon; Ha-Vy Truong; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2012-06-25       Impact factor: 5.191

Review 3.  Mechanisms of resistance and clinical relevance of resistance to β-lactams, glycopeptides, and fluoroquinolones.

Authors:  Louis B Rice
Journal:  Mayo Clin Proc       Date:  2012-02       Impact factor: 7.616

4.  A rapid matrix-assisted laser desorption ionization-time of flight mass spectrometry-based method for single-plasmid tracking in an outbreak of carbapenem-resistant Enterobacteriaceae.

Authors:  Anna F Lau; Honghui Wang; Rebecca A Weingarten; Steven K Drake; Anthony F Suffredini; Mark K Garfield; Yong Chen; Marjan Gucek; Jung-Ho Youn; Frida Stock; Hanna Tso; Jim DeLeo; James J Cimino; Karen M Frank; John P Dekker
Journal:  J Clin Microbiol       Date:  2014-05-21       Impact factor: 5.948

5.  Global Dissemination of blaKPC into Bacterial Species beyond Klebsiella pneumoniae and In Vitro Susceptibility to Ceftazidime-Avibactam and Aztreonam-Avibactam.

Authors:  Krystyna M Kazmierczak; Douglas J Biedenbach; Meredith Hackel; Sharon Rabine; Boudewijn L M de Jonge; Samuel K Bouchillon; Daniel F Sahm; Patricia A Bradford
Journal:  Antimicrob Agents Chemother       Date:  2016-07-22       Impact factor: 5.191

6.  Epidemiology of carbapenem resistant Enterobacteriaceae (CRE) during 2000-2012 in Asia.

Authors:  Yanling Xu; Bing Gu; Mao Huang; Haiyan Liu; Ting Xu; Wenying Xia; Tong Wang
Journal:  J Thorac Dis       Date:  2015-03       Impact factor: 2.895

7.  Interplay among IncA and bla KPC-Carrying Plasmids in Citrobacter freundii.

Authors:  Ibrahim Bitar; Mariasofia Caltagirone; Laura Villa; Vittoria Mattioni Marchetti; Elisabetta Nucleo; Mario Sarti; Roberta Migliavacca; Alessandra Carattoli
Journal:  Antimicrob Agents Chemother       Date:  2019-04-25       Impact factor: 5.191

8.  Translocation of Carbapenemase Gene blaKPC-2 both Internal and External to Transposons Occurs via Novel Structures of Tn1721 and Exhibits Distinct Movement Patterns.

Authors:  Yu Tang; Gang Li; Wei Liang; Pinghua Shen; Ying Zhang; Xiaofei Jiang
Journal:  Antimicrob Agents Chemother       Date:  2017-09-22       Impact factor: 5.191

9.  Unlocking Tn3-family transposase activity in vitro unveils an asymetric pathway for transposome assembly.

Authors:  Emilien Nicolas; Cédric A Oger; Nathan Nguyen; Michaël Lambin; Amandine Draime; Sébastien C Leterme; Michael Chandler; Bernard F J Hallet
Journal:  Proc Natl Acad Sci U S A       Date:  2017-01-17       Impact factor: 11.205

10.  Genomic Epidemiology of Complex, Multispecies, Plasmid-Borne bla KPC Carbapenemase in Enterobacterales in the United Kingdom from 2009 to 2014.

Authors:  Nicole Stoesser; Hang T T Phan; Anna C Seale; Zoie Aiken; Stephanie Thomas; Matthew Smith; David Wyllie; Ryan George; Robert Sebra; Amy J Mathers; Alison Vaughan; Timothy E A Peto; Matthew J Ellington; Katie L Hopkins; Derrick W Crook; Alex Orlek; William Welfare; Julie Cawthorne; Cheryl Lenney; Andrew Dodgson; Neil Woodford; A Sarah Walker
Journal:  Antimicrob Agents Chemother       Date:  2020-04-21       Impact factor: 5.191
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.