INTRODUCTION: This study aimed to describe the structural pulmonary sequelae of bronchopulmonary dysplasia (BPD) in adulthood. SUBJECTS AND METHODS: Fifty-one adult survivors (36 females and 15 males; median age 20 years) of BPD underwent high-resolution inspiratory and expiratory computed tomography of the chest. The scans were evaluated independently by two thoracic radiologists blinded to the patient's clinical details using a standardised scoring system. RESULTS: Abnormal findings were seen in 50 (98%), the most common of which were subpleural triangular opacities (94%), linear opacities (90%), air trapping (65%) and emphysema (47%). The kappa values were derived by simplifying the score for each finding as present or absent. The kappa values for these findings were 0.65, 0.20, 0.58 and 0.54, respectively. CONCLUSIONS: Common findings were triangular, linear opacities and gas trapping. Emphysema diagnosis was more prevalent than previous studies, which may have been enhanced by improved technical factors.
INTRODUCTION: This study aimed to describe the structural pulmonary sequelae of bronchopulmonary dysplasia (BPD) in adulthood. SUBJECTS AND METHODS: Fifty-one adult survivors (36 females and 15 males; median age 20 years) of BPD underwent high-resolution inspiratory and expiratory computed tomography of the chest. The scans were evaluated independently by two thoracic radiologists blinded to the patient's clinical details using a standardised scoring system. RESULTS: Abnormal findings were seen in 50 (98%), the most common of which were subpleural triangular opacities (94%), linear opacities (90%), air trapping (65%) and emphysema (47%). The kappa values were derived by simplifying the score for each finding as present or absent. The kappa values for these findings were 0.65, 0.20, 0.58 and 0.54, respectively. CONCLUSIONS: Common findings were triangular, linear opacities and gas trapping. Emphysema diagnosis was more prevalent than previous studies, which may have been enhanced by improved technical factors.
Authors: Jessica Y Islam; Roberta L Keller; Judy L Aschner; Tina V Hartert; Paul E Moore Journal: Am J Respir Crit Care Med Date: 2015-07-15 Impact factor: 21.405
Authors: Sabina Strashun; Joanna Seliga-Siwecka; Roberto Chioma; Kinga Zielińska; Krzysztof Włodarczyk; Eduardo Villamor; Roy K Philip; Niazy Al Assaf; Maria Pierro Journal: BMJ Open Date: 2022-06-15 Impact factor: 3.006
Authors: Anke Kindermann; Leonore Binder; Jan Baier; Beate Gündel; Andreas Simm; Roland Haase; Babett Bartling Journal: BMC Pulm Med Date: 2019-12-16 Impact factor: 3.317
Authors: Fumihiko Namba; Hayato Go; Jennifer A Murphy; Ping La; Guang Yang; Shaon Sengupta; Amal P Fernando; Mekdes Yohannes; Chhanda Biswas; Suzanne L Wehrli; Phyllis A Dennery Journal: PLoS One Date: 2014-03-05 Impact factor: 3.240