Literature DB >> 21842439

Chancroid transmission dynamics: a mathematical modeling approach.

C P Bhunu1, S Mushayabasa.   

Abstract

Mathematical models have long been used to better understand disease transmission dynamics and how to effectively control them. Here, a chancroid infection model is presented and analyzed. The disease-free equilibrium is shown to be globally asymptotically stable when the reproduction number is less than unity. High levels of treatment are shown to reduce the reproduction number suggesting that treatment has the potential to control chancroid infections in any given community. This result is also supported by numerical simulations which show a decline in chancroid cases whenever the reproduction number is less than unity.

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Year:  2011        PMID: 21842439     DOI: 10.1007/s12064-011-0132-1

Source DB:  PubMed          Journal:  Theory Biosci        ISSN: 1431-7613            Impact factor:   1.919


  15 in total

1.  Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission.

Authors:  P van den Driessche; James Watmough
Journal:  Math Biosci       Date:  2002 Nov-Dec       Impact factor: 2.144

2.  A theoretical assessment of the effects of smoking on the transmission dynamics of tuberculosis.

Authors:  C P Bhunu; S Mushayabasa; J M Tchuenche
Journal:  Bull Math Biol       Date:  2010-08-20       Impact factor: 1.758

Review 3.  Treatment of chancroid with azithromycin.

Authors:  R C Ballard; H Ye; A Matta; Y Dangor; F Radebe
Journal:  Int J STD AIDS       Date:  1996       Impact factor: 1.359

4.  Prevention of experimental Haemophilus ducreyi infection: a randomized, controlled clinical trial.

Authors:  A C Thornton; E M O'Mara; S J Sorensen; T J Hiltke; K Fortney; B Katz; R E Shoup; A F Hood; S M Spinola
Journal:  J Infect Dis       Date:  1998-06       Impact factor: 5.226

5.  A randomized, double-blind, placebo-controlled trial of single-dose ciprofloxacin versus erythromycin for the treatment of chancroid in Nairobi, Kenya.

Authors:  I M Malonza; M W Tyndall; J O Ndinya-Achola; I Maclean; S Omar; K S MacDonald; J Perriens; K Orle; F A Plummer; A R Ronald; S Moses
Journal:  J Infect Dis       Date:  1999-12       Impact factor: 5.226

6.  Accuracy of clinical diagnosis of genital ulcer disease.

Authors:  Y Dangor; R C Ballard; F da L Exposto; G Fehler; S D Miller; H J Koornhof
Journal:  Sex Transm Dis       Date:  1990 Oct-Dec       Impact factor: 2.830

7.  Dynamical behavior of a hepatitis B virus transmission model with vaccination.

Authors:  Jianhua Pang; Jing-an Cui; Xueyong Zhou
Journal:  J Theor Biol       Date:  2010-06-08       Impact factor: 2.691

8.  Eradicating chancroid.

Authors:  R Steen
Journal:  Bull World Health Organ       Date:  2001-10-23       Impact factor: 9.408

9.  Genital ulcer disease: accuracy of clinical diagnosis and strategies to improve control in Durban, South Africa.

Authors:  N O'Farrell; A A Hoosen; K D Coetzee; J van den Ende
Journal:  Genitourin Med       Date:  1994-02

10.  Fleroxacin in the treatment of chancroid: an open study in men seropositive or seronegative for the human immunodeficiency virus type 1.

Authors:  M W Tyndall; P J Plourde; E Agoki; W Malisa; J O Ndinya-Achola; F A Plummer; A R Ronald
Journal:  Am J Med       Date:  1993-03-22       Impact factor: 4.965

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