Literature DB >> 21842148

Management of parapharyngeal giant pleomorphic adenoma.

Pedro Infante-Cossio1, Eduardo Gonzalez-Cardero, Luis-Miguel Gonzalez-Perez, Manuel Leopoldo-Rodado, Alberto Garcia-Perla, Francisco Esteban.   

Abstract

INTRODUCTION: Pleomorphic adenoma (PA) is found rarely in the parapharyngeal space (PPS). Because of late diagnosis due to slow growth, close proximity to vital neurovascular structures and risks of surgery, it poses a great difficulty for both diagnosis and surgical management. The preferred surgical approach to the PPS is the cervical-transparotid including a total parotidectomy with facial nerve preservation combined with a cervical access for dissection of cranial nerves and vascular structures thus allowing a safe removal of the tumor together with the parotid deep lobe. We report herein our experience in the management of giant PAs involving the prestyloid PPS and describe a not well-documented transparotid route by preservation of the parotid superficial lobe in combination with an intraoral approach. PATIENTS AND METHODS: In this retrospective study, three cases of patients having giant PAs involving the PPS are evaluated. All patients had signs of foreign body sensation in the throat and a growing mass bulging in the oropharynx. Diagnosis was based on MRI and upon preoperative intraoral biopsy. The average tumor size was 5.7 cm. Patients underwent surgery and excision of tumors via transparotid-intraoral approach. In two cases, the superficial lobe was preserved and afterwards put back in its anatomic location.
RESULTS: All patients were discharged without complications, and no recurrences were observed.
CONCLUSIONS: Preoperative diagnosis management of PPS giant tumors should be based on imaging and upon open transoral biopsy if possible. The transparotid-intraoral approach provided adequate visibility to remove large PAs involving the prestyloid PPS.

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Mesh:

Year:  2011        PMID: 21842148     DOI: 10.1007/s10006-011-0289-2

Source DB:  PubMed          Journal:  Oral Maxillofac Surg        ISSN: 1865-1550


  23 in total

1.  Pleomorphic adenoma and severe obstructive sleep apnoea.

Authors:  C E B Giddings; D Bray; J Rimmer; P Williamson
Journal:  J Laryngol Otol       Date:  2005-03       Impact factor: 1.469

2.  Parotid function after selective deep lobe parotidectomy.

Authors:  Giuseppe Colella; Amerigo Giudice; PierFrancesco Rambaldi; Vincenzo Cuccurullo
Journal:  Br J Oral Maxillofac Surg       Date:  2006-06-19       Impact factor: 1.651

3.  Preservation of the superficial lobe with tumours of the deep-lobe of the parotid.

Authors:  C M E Avery; K Fleming; C J Siegmund
Journal:  Br J Oral Maxillofac Surg       Date:  2006-10-04       Impact factor: 1.651

4.  Deep-lobe parotid tumor presenting in the parapharyngeal space.

Authors:  Sofia Avitia; Jason S Hamilton; Ryan F Osborne
Journal:  Ear Nose Throat J       Date:  2007-12       Impact factor: 1.697

5.  Magnetic resonance imaging and the management of parapharyngeal space tumors.

Authors:  F R Miller; J R Wanamaker; P Lavertu; B G Wood
Journal:  Head Neck       Date:  1996 Jan-Feb       Impact factor: 3.147

6.  The role of pre-operative CT-guided FNAB for parapharyngeal space tumors.

Authors:  Tarik Y Farrag; Frank R Lin; Wayne M Koch; Joseph A Califano; Charles W Cummings; Maryam A Farinola; Ralph P Tufano
Journal:  Otolaryngol Head Neck Surg       Date:  2007-03       Impact factor: 3.497

7.  Safety and efficacy of transcervical resection of parapharyngeal space neoplasms.

Authors:  J P Malone; A Agrawal; D E Schuller
Journal:  Ann Otol Rhinol Laryngol       Date:  2001-12       Impact factor: 1.547

8.  Surgical management of parapharyngeal space tumours: results of 10-year follow-up.

Authors:  F Bozza; M G Vigili; P Ruscito; A Marzetti; F Marzetti
Journal:  Acta Otorhinolaryngol Ital       Date:  2009-02       Impact factor: 2.124

9.  Parapharyngeal space neoplasms.

Authors:  K V Hughes; K D Olsen; T V McCaffrey
Journal:  Head Neck       Date:  1995 Mar-Apr       Impact factor: 3.147

Review 10.  Surgical treatment of benign parapharyngeal space tumours. Presentation of two clinical cases and revision of the literature.

Authors:  Martin Fernández Ferro; Jacinto Fernández Sanromán; Alberto Costas López; Jesús Sandoval Gutiérrez; Annahys López de Sánchez
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2008-01-01
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  5 in total

1.  Prestyloid compartment of the parapharyngeal space: a histological study using late-stage human fetuses.

Authors:  Yukio Katori; Tatsuaki Kawase; Kwang Ho Cho; Hiroshi Abe; Jose Francisco Rodríguez-Vázquez; Gen Murakami; Shinichi Abe
Journal:  Surg Radiol Anat       Date:  2012-05-11       Impact factor: 1.246

2.  Giant de novo pleomorphic adenoma arising from the parapharyngeal space.

Authors:  Sang Hwang; Sim Choroomi; Ben McArdle; Ian Jacobson
Journal:  Case Rep Otolaryngol       Date:  2013-12-12

3.  Largest De Novo Parapharyngeal Pleomorphic Adenoma: A Rare Case Removed Via Minimal Access Approach.

Authors:  Vikas Malhotra; Nikhil Arora; Varun Rai
Journal:  Ann Maxillofac Surg       Date:  2017 Jan-Jun

4.  Complications after superficial parotidectomy for pleomorphic adenoma.

Authors:  P Infante-Cossio; E Gonzalez-Cardero; A Garcia-Perla-Garcia; E Montes-Latorre; J-L Gutierrez-Perez; V-E Prats-Golczer
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2018-07-01

5.  The transcervical approach for parapharyngeal space pleomorphic adenomas: indications and technique.

Authors:  Gilad Horowitz; Oded Ben-Ari; Oshri Wasserzug; Noam Weizman; Moshe Yehuda; Dan M Fliss
Journal:  PLoS One       Date:  2014-02-27       Impact factor: 3.240

  5 in total

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