Literature DB >> 21841524

Correlation between persistent neurological impairment and clinical outcome after microdiscectomy for treatment of lumbar disc herniation.

Orlando Righesso1, Asdrubal Falavigna, Osmar Avanzi.   

Abstract

BACKGROUND: Outcome of lumbar disc herniation is often based on clinical scores and less frequently on the neurological examination. However, even when clinical outcome measures are favorable, patients may still experience motor or sensory impairment.
OBJECTIVE: To evaluate the percentage of patients with persistent neurological deficits after lumbar disc surgery and whether these correlate with clinical outcome.
METHODS: A total of 150 patients with sciatica and lumbar disc herniation with neurological impairment underwent microdiscectomy and were prospectively followed for 24 months. Patients were assessed pre- and postoperatively with neurological examination, the Oswestry Disability Index (ODI), and the visual analog scale (VAS) for pain.
RESULTS: Twenty-four months after surgery, 25% of patients who presented with motor deficits, 40% of patients with sensory deficits, and 48% of patients with reflex abnormalities remained unchanged. The VAS and the ODI showed significant improvement in both patients with and without persistent neurological impairment immediately after surgical repair of the herniated disc with progressive improvement over the follow-up period. However, when calculating the area under the receiver operating characteristics curve, no statistically significant correlation could be established between the presence and persistence of neurological impairment and the 2 clinical scores.
CONCLUSION: There seems to be no correlation between clinical results and neurological impairment when assessed by the VAS and ODI.

Entities:  

Mesh:

Year:  2012        PMID: 21841524     DOI: 10.1227/NEU.0b013e318231da4c

Source DB:  PubMed          Journal:  Neurosurgery        ISSN: 0148-396X            Impact factor:   4.654


  5 in total

1.  Multidimensional long-term outcome analysis after single-level lumbar microdiscectomy: a retrospective single-centre study.

Authors:  Sebastian A Ahmadi; Ilja-Paul Burkert; Hans-Jakob Steiger; Sven Oliver Eicker
Journal:  Eur J Orthop Surg Traumatol       Date:  2017-10-03

2.  Effects of swimming on pain and inflammatory factors in rats with lumbar disc herniation.

Authors:  Yizhuan Huang; Zhendong Zhong; Dandan Yang; Lingyuan Huang; Fengjiao Hu; Dan Luo; Linxia Yan; Rong Wang; Lijie Zhang; Xuemei Hu; Jinli He
Journal:  Exp Ther Med       Date:  2019-08-14       Impact factor: 2.751

3.  Lower Extremity Motor Deficits Are Underappreciated in Patient-Reported Outcome Measures: Added Value of Objective Outcome Measures.

Authors:  Martin Nikolaus Stienen; Nicolai Maldaner; Marketa Sosnova; Holger Joswig; Marco Vincenzo Corniola; Luca Regli; Gerhard Hildebrandt; Karl Schaller; Oliver Pascal Gautschi
Journal:  Neurospine       Date:  2020-01-26

4.  A Noninvasive Assistant System in Diagnosis of Lumbar Disc Herniation.

Authors:  Miodrag Peulić; Miloš Joković; Tijana Šušteršič; Aleksandar Peulić
Journal:  Comput Math Methods Med       Date:  2020-04-03       Impact factor: 2.238

5.  TNFAIP3 alleviates pain in lumbar disc herniation rats by inhibiting the NF-κB pathway.

Authors:  Zhaohui Xie; Jixiang Chen; Zhengjun Xiao; Yuqin Li; Tao Yuan; Yandong Li
Journal:  Ann Transl Med       Date:  2022-01
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.