| Literature DB >> 21841075 |
Ramón Latorre1, Sebastián Brauchi, Rodolfo Madrid, Patricio Orio.
Abstract
Transient receptor potential melastatin 8 (TRPM8), a calcium-permeable cation channel activated by cold, cooling compounds and voltage, is the main molecular entity responsible for detection of cold temperatures in the somatosensory system. Here, we review the biophysical properties, physiological role, and near-membrane trafficking of this exciting polymodal ion channel.Entities:
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Year: 2011 PMID: 21841075 DOI: 10.1152/physiol.00004.2011
Source DB: PubMed Journal: Physiology (Bethesda) ISSN: 1548-9221