Literature DB >> 2184093

Estimation of individual genetic and environmental factor scores.

D I Boomsma1, P C Molenaar, J F Orlebeke.   

Abstract

Implicit in the application of the common-factor model as a method for decomposing trait covariance into a genetic and environmental part is the use of factor scores. In multivariate analyses, it is possible to estimate these factor scores for the communal part of the model. Estimation of scores on latent factors in terms of individual observations within the context of a twin/family study amounts to estimation of individual genetic and environmental scores. Such estimates may be of both theoretical and practical interest and may be provided with confidence intervals around the individual estimates. The method is first illustrated with stimulated twin data and next is applied to blood pressure data obtained in a Dutch sample of 59 male adolescent twin pairs. Subjects with high blood pressure can be distinguished into groups with high genetic or high environmental scores.

Mesh:

Year:  1990        PMID: 2184093     DOI: 10.1002/gepi.1370070115

Source DB:  PubMed          Journal:  Genet Epidemiol        ISSN: 0741-0395            Impact factor:   2.135


  11 in total

1.  The nature of schizotypy among multigenerational multiplex schizophrenia families.

Authors:  Sarah I Tarbox; Laura Almasy; Raquel E Gur; Vishwajit L Nimgaonkar; Michael F Pogue-Geile
Journal:  J Abnorm Psychol       Date:  2012-01-30

2.  Decomposition of multivariate phenotypic means in multigroup genetic covariance structure analysis.

Authors:  C V Dolan; P C Molenaar; D I Boomsma
Journal:  Behav Genet       Date:  1992-05       Impact factor: 2.805

3.  Estimation of individual genetic and environmental profiles in longitudinal designs.

Authors:  D I Boomsma; P C Molenaar; C V Dolan
Journal:  Behav Genet       Date:  1991-05       Impact factor: 2.805

4.  Using multivariate genetic modeling to detect pleiotropic quantitative trait loci.

Authors:  D I Boomsma
Journal:  Behav Genet       Date:  1996-03       Impact factor: 2.805

5.  Could a continuous measure of individual transmissible risk be useful in clinical assessment of substance use disorder? Findings from the National Epidemiological Survey on Alcohol and Related Conditions.

Authors:  Ty A Ridenour; Levent Kirisci; Ralph E Tarter; Michael M Vanyukov
Journal:  Drug Alcohol Depend       Date:  2011-06-29       Impact factor: 4.492

6.  Developmental Endophenotypes: Indexing Genetic Risk for Substance Abuse with the P300 Brain Event-Related Potential.

Authors:  William G Iacono; Stephen M Malone
Journal:  Child Dev Perspect       Date:  2011-12-01

7.  Simultaneous genetic analysis of means and covariance structure: Pearson-Lawley selection rules.

Authors:  C V Dolan; P C Molenaar; D I Boomsma
Journal:  Behav Genet       Date:  1994-01       Impact factor: 2.805

Review 8.  A third source of developmental differences.

Authors:  P C Molenaar; D I Boomsma; C V Dolan
Journal:  Behav Genet       Date:  1993-11       Impact factor: 2.805

9.  Heritability and molecular-genetic basis of the P3 event-related brain potential: a genome-wide association study.

Authors:  Stephen M Malone; Uma Vaidyanathan; Saonli Basu; Michael B Miller; Matt McGue; William G Iacono
Journal:  Psychophysiology       Date:  2014-12       Impact factor: 4.016

10.  Genetic covariance structure of the four main features of borderline personality disorder.

Authors:  Marijn A Distel; Gonneke Willemsen; Lannie Ligthart; Catherine A Derom; Nicholas G Martin; Michael C Neale; Timothy J Trull; Dorret I Boomsma
Journal:  J Pers Disord       Date:  2010-08
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.