Literature DB >> 21840479

We contain multitudes: the protean face of retinoblastoma.

Seth Blackshaw1.   

Abstract

The precise cellular characteristics of retinoblastoma have long been debated. In this issue of Cancer Cell, McEvoy et al. reveal that retinoblastomas are highly homogeneous at the molecular level and coexpress genes characteristic of retinal progenitors and various different mature retinal cell types, while ultrastructurally resembling amacrine cells.
Copyright © 2011 Elsevier Inc. All rights reserved.

Entities:  

Year:  2011        PMID: 21840479      PMCID: PMC3212430          DOI: 10.1016/j.ccr.2011.08.002

Source DB:  PubMed          Journal:  Cancer Cell        ISSN: 1535-6108            Impact factor:   31.743


  10 in total

Review 1.  Transcriptional regulation of photoreceptor development and homeostasis in the mammalian retina.

Authors:  Anand Swaroop; Douglas Kim; Douglas Forrest
Journal:  Nat Rev Neurosci       Date:  2010-08       Impact factor: 34.870

2.  Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice.

Authors:  Itsuki Ajioka; Rodrigo A P Martins; Ildar T Bayazitov; Stacy Donovan; Dianna A Johnson; Sharon Frase; Samantha A Cicero; Kelli Boyd; Stanislav S Zakharenko; Michael A Dyer
Journal:  Cell       Date:  2007-10-19       Impact factor: 41.582

3.  Cytotoxic effects of antipsychotic drugs implicate cholesterol homeostasis as a novel chemotherapeutic target.

Authors:  Erik D Wiklund; Vibeke S Catts; Stanley V Catts; Teng Fong Ng; Noel J Whitaker; Andrew J Brown; Louise H Lutze-Mann
Journal:  Int J Cancer       Date:  2010-01-01       Impact factor: 7.396

4.  Coexpression of normally incompatible developmental pathways in retinoblastoma genesis.

Authors:  Justina McEvoy; Jacqueline Flores-Otero; Jiakun Zhang; Katie Nemeth; Rachel Brennan; Cori Bradley; Fred Krafcik; Carlos Rodriguez-Galindo; Matthew Wilson; Shunbin Xiong; Guillermina Lozano; Julien Sage; Ligia Fu; Lotfi Louhibi; Jeff Trimarchi; Amar Pani; Richard Smeyne; Dianna Johnson; Michael A Dyer
Journal:  Cancer Cell       Date:  2011-08-16       Impact factor: 31.743

5.  Rb regulates fate choice and lineage commitment in vivo.

Authors:  Eliezer Calo; Jose A Quintero-Estades; Paul S Danielian; Simona Nedelcu; Seth D Berman; Jacqueline A Lees
Journal:  Nature       Date:  2010-08-04       Impact factor: 49.962

Review 6.  Recent advances in retinoblastoma genetic research.

Authors:  Kim E Nichols; Susan Walther; Elizabeth Chao; Carol Shields; Arupa Ganguly
Journal:  Curr Opin Ophthalmol       Date:  2009-09       Impact factor: 3.761

7.  Retinoblastoma has properties of a cone precursor tumor and depends upon cone-specific MDM2 signaling.

Authors:  Xiaoliang L Xu; Yuqiang Fang; Thomas C Lee; Douglas Forrest; Cheryl Gregory-Evans; Dena Almeida; Aihong Liu; Suresh C Jhanwar; David H Abramson; David Cobrinik
Journal:  Cell       Date:  2009-06-12       Impact factor: 41.582

8.  Differential gene expression profile of retinoblastoma compared to normal retina.

Authors:  Arupa Ganguly; Carol L Shields
Journal:  Mol Vis       Date:  2010-07-13       Impact factor: 2.367

9.  Genomic analysis of mouse retinal development.

Authors:  Seth Blackshaw; Sanjiv Harpavat; Jeff Trimarchi; Li Cai; Haiyan Huang; Winston P Kuo; Griffin Weber; Kyungjoon Lee; Rebecca E Fraioli; Seo-Hee Cho; Rachel Yung; Elizabeth Asch; Lucila Ohno-Machado; Wing H Wong; Constance L Cepko
Journal:  PLoS Biol       Date:  2004-06-29       Impact factor: 8.029

10.  Individual retinal progenitor cells display extensive heterogeneity of gene expression.

Authors:  Jeffrey M Trimarchi; Michael B Stadler; Constance L Cepko
Journal:  PLoS One       Date:  2008-02-13       Impact factor: 3.240

  10 in total

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