Literature DB >> 21839968

Adjuvant temozolomide chemotherapy for treatment of papillary tumor of the pineal region.

Martin Lorenzetti1, Federica Motta, Rolando Campanella, Dario Bauer, Agnese Assi, Cesare Arienta, Sergio Maria Gaini, Manuela Caroli.   

Abstract

BACKGROUND: We present a personal case of papillary pineocytoma in a 42-year-old woman.
METHODS: The lesion was first treated surgically both for diagnostic aims and for resolution of the mass effect causing hydrocephalus and correlated neurological disturbances. Because the tumor recurred after surgery and radiotherapy, we decided to further treat the patient with chemotherapy, in particular with temozolomide.
RESULTS: Currently, almost 9 years after the first treatment, the patient is symptom-free and follow-up magnetic resonance imaging shows no tumor recurrence.
CONCLUSION: Although surgery should be considered the first-choice therapy, we think that temozolomide can be a valid option in case of recurrence of these rare tumors.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 21839968     DOI: 10.1016/j.wneu.2010.10.039

Source DB:  PubMed          Journal:  World Neurosurg        ISSN: 1878-8750            Impact factor:   2.104


  4 in total

1.  Papillary tumor of the pineal region: a single-center experience.

Authors:  Christian Malte Boßelmann; Irina Gepfner-Tuma; Jens Schittenhelm; Cornelia Brendle; Juergen Honegger; Ghazaleh Tabatabai
Journal:  Neurooncol Pract       Date:  2020-04-03

2.  Role of surgery, radiotherapy and chemotherapy in papillary tumors of the pineal region: a multicenter study.

Authors:  F Fauchon; M Hasselblatt; A Jouvet; J Champier; M Popovic; R Kirollos; T Santarius; S Amemiya; T Kumabe; D Frappaz; M Lonjon; M Fèvre Montange; A Vasiljevic
Journal:  J Neurooncol       Date:  2013-01-12       Impact factor: 4.130

3.  Bevacizumab is Effective for Recurrent Papillary Tumor of the Pineal Region: First Report.

Authors:  Adam L Cohen; Karen Salzman; Cheryl Palmer; Randy Jensen; Howard Colman
Journal:  Case Rep Oncol       Date:  2013-08-24

4.  Papillary tumor of the pineal region with extended clinical and radiologic follow-up.

Authors:  Hakeem J Shakir; Jingxin Qiu; Dheerendra Prasad; Laszlo L Mechtler; Robert A Fenstermaker
Journal:  Surg Neurol Int       Date:  2015-10-07
  4 in total

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