| Literature DB >> 21837806 |
Anna Papa1, Dimitra Karabaxoglou, Athina Kansouzidou.
Abstract
Cross-reactions in serology are common among flaviviruses. During the outbreak of West Nile virus (WNV) infections in Greece in 2010, WNV IgM-positive serum and cerebrospinal fluid samples were tested for the presence of IgM and IgG antibodies against Dengue virus (DENV) and tick-borne encephalitis virus. Higher cross-reactivity was observed in IgM antibodies between WNV and DENV; however, the index of the WNV antibodies was in all cases higher than that of the DENV antibodies. There is a need for caution when evaluating serologic results of flaviviral infections, while efforts have to be focused on the development of diagnostic assays with increased specificity.Entities:
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Year: 2011 PMID: 21837806 DOI: 10.1002/jmv.22180
Source DB: PubMed Journal: J Med Virol ISSN: 0146-6615 Impact factor: 2.327