Literature DB >> 2183539

Enhanced vasoconstrictor effect of endothelin in cerebral arteries from rats with subarachnoid haemorrhage.

C Alafaci1, I Jansen, M A Arbab, Y Shiokawa, N A Svendgaard, L Edvinsson.   

Abstract

The contractile response to endothelin has been examined in cerebral arteries from rats subjected to a prior subarachnoid haemorrhage (SAH) and compared with saline-injected controls. Endothelin elicited concentration-dependent contractions of rat basilar artery segments. The endothelin-induced contractions were much stronger in the SAH compared to control animals, which suggests a role in the pathophysiology of cerebral vasospasm.

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Year:  1990        PMID： 2183539     DOI： 10.1111/j.1748-1716.1990.tb08852.x

Source DB:  PubMed          Journal:  Acta Physiol Scand        ISSN： 0001-6772


  4 in total

1.  Mechanisms underlying potentiation of endothelin-1-induced myofilament Ca(2+) sensitization after subarachnoid hemorrhage.

Authors:  Yuichiro Kikkawa; Satoshi Matsuo; Katsuharu Kameda; Mayumi Hirano; Akira Nakamizo; Tomio Sasaki; Katsuya Hirano
Journal:  J Cereb Blood Flow Metab       Date:  2011-09-28       Impact factor: 6.200

Review 2.  The clinical potential of endothelin receptor antagonists in cardiovascular medicine.

Authors:  C J Ferro; D J Webb
Journal:  Drugs       Date:  1996-01       Impact factor: 9.546

3.  Inhibition of cerebral vasoconstriction by dantrolene and nimodipine.

Authors:  Salvatore Salomone; Guray Soydan; Michael A Moskowitz; John Randall Sims
Journal:  Neurocrit Care       Date:  2008-10-16       Impact factor: 3.210

4.  Protein kinase mediated upregulation of endothelin A, endothelin B and 5-hydroxytryptamine 1B/1D receptors during organ culture in rat basilar artery.

Authors:  Jacob Hansen-Schwartz; Carl-Lennart Svensson; Cang-Bao Xu; Lars Edvinsson
Journal:  Br J Pharmacol       Date:  2002-09       Impact factor: 8.739
  4 in total

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