Literature DB >> 21835335

Tracking down the molecular substrates of stress: new roles for p38α MAPK and kappa-opioid receptors.

John W Muschamp1, Ashlee Van't Veer, William A Carlezon.   

Abstract

In this issue, Bruchas et al. (2011) uncover a novel stress-induced p38α MAPK signaling cascade within serotonergic neurons of the dorsal raphe nucleus that mediates depressive and drug-seeking behaviors. Their findings have potentially important implications for medication development.
Copyright © 2011 Elsevier Inc. All rights reserved.

Entities:  

Year:  2011        PMID： 21835335      PMCID： PMC3155977          DOI： 10.1016/j.neuron.2011.07.018

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  15 in total

Review 1.  A neurotrophic model for stress-related mood disorders.

Authors:  Ronald S Duman; Lisa M Monteggia
Journal:  Biol Psychiatry       Date:  2006-04-21       Impact factor: 13.382

2.  Selective p38α MAPK deletion in serotonergic neurons produces stress resilience in models of depression and addiction.

Authors:  Michael R Bruchas; Abigail G Schindler; Haripriya Shankar; Daniel I Messinger; Mayumi Miyatake; Benjamin B Land; Julia C Lemos; Catherine E Hagan; John F Neumaier; Albert Quintana; Richard D Palmiter; Charles Chavkin
Journal:  Neuron       Date:  2011-08-11       Impact factor: 17.173

Review 3.  Functional selectivity and classical concepts of quantitative pharmacology.

Authors:  Jonathan D Urban; William P Clarke; Mark von Zastrow; David E Nichols; Brian Kobilka; Harel Weinstein; Jonathan A Javitch; Bryan L Roth; Arthur Christopoulos; Patrick M Sexton; Keith J Miller; Michael Spedding; Richard B Mailman
Journal:  J Pharmacol Exp Ther       Date:  2006-06-27       Impact factor: 4.030

4.  Kappa opioid receptor signaling in the basolateral amygdala regulates conditioned fear and anxiety in rats.

Authors:  Allison T Knoll; John W Muschamp; Stephanie E Sillivan; Deveroux Ferguson; David M Dietz; Edward G Meloni; F Ivy Carroll; Eric J Nestler; Christine Konradi; William A Carlezon
Journal:  Biol Psychiatry       Date:  2011-04-30       Impact factor: 13.382

Review 5.  Role of CRF receptor signaling in stress vulnerability, anxiety, and depression.

Authors:  Richard L Hauger; Victoria Risbrough; Robert H Oakley; J Alberto Olivares-Reyes; Frank M Dautzenberg
Journal:  Ann N Y Acad Sci       Date:  2009-10       Impact factor: 5.691

Review 6.  Biological substrates of reward and aversion: a nucleus accumbens activity hypothesis.

Authors:  William A Carlezon; Mark J Thomas
Journal:  Neuropharmacology       Date:  2008-07-15       Impact factor: 5.250

7.  Multiple opiate receptors: [3H]ethylketocyclazocine receptor binding and ketocyclazocine analgesia.

Authors:  G W Pasternak
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

Review 8.  The revised monoamine theory of depression: a modulatory role for monoamines, based on new findings from monoamine depletion experiments in humans.

Authors:  G R Heninger; P L Delgado; D S Charney
Journal:  Pharmacopsychiatry       Date:  1996-01       Impact factor: 5.788

9.  Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking.

Authors:  Benjamin B Land; Michael R Bruchas; Selena Schattauer; William J Giardino; Megumi Aita; Daniel Messinger; Thomas S Hnasko; Richard D Palmiter; Charles Chavkin
Journal:  Proc Natl Acad Sci U S A       Date:  2009-10-28       Impact factor: 11.205

10.  Activation of raphe efferents to the medial prefrontal cortex by corticotropin-releasing factor: correlation with anxiety-like behavior.

Authors:  Edward G Meloni; Catherine L Reedy; Bruce M Cohen; William A Carlezon
Journal:  Biol Psychiatry       Date:  2007-12-03       Impact factor: 13.382
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  7 in total

Review 1.  Salvinorin A analogs and other κ-opioid receptor compounds as treatments for cocaine abuse.

Authors:  Bronwyn M Kivell; Amy W M Ewald; Thomas E Prisinzano
Journal:  Adv Pharmacol       Date:  2014

Review 2.  Molecular mechanisms of opioid receptor-dependent signaling and behavior.

Authors:  Ream Al-Hasani; Michael R Bruchas
Journal:  Anesthesiology       Date:  2011-12       Impact factor: 7.892

Review 3.  Toward a Better Understanding of the Mechanisms and Pathophysiology of Anhedonia: Are We Ready for Translation?

Authors:  Diego A Pizzagalli
Journal:  Am J Psychiatry       Date:  2022-07       Impact factor: 19.242

Review 4.  Development of κ opioid receptor antagonists.

Authors:  F Ivy Carroll; William A Carlezon
Journal:  J Med Chem       Date:  2013-02-14       Impact factor: 7.446

5.  Corticotropin-releasing factor (CRF)-induced disruption of attention in rats is blocked by the κ-opioid receptor antagonist JDTic.

Authors:  Ashlee Van't Veer; Jessica M Yano; F Ivy Carroll; Bruce M Cohen; William A Carlezon
Journal:  Neuropsychopharmacology       Date:  2012-09-05       Impact factor: 7.853

6.  Selective kappa-opioid antagonism ameliorates anhedonic behavior: evidence from the Fast-fail Trial in Mood and Anxiety Spectrum Disorders (FAST-MAS).

Authors:  Diego A Pizzagalli; Moria Smoski; Yuen-Siang Ang; Alexis E Whitton; Gerard Sanacora; Sanjay J Mathew; John Nurnberger; Sarah H Lisanby; Dan V Iosifescu; James W Murrough; Hongqiu Yang; Richard D Weiner; Joseph R Calabrese; Wayne Goodman; William Z Potter; Andrew D Krystal
Journal:  Neuropsychopharmacology       Date:  2020-06-16       Impact factor: 7.853

7.  Pharmacology and anti-addiction effects of the novel κ opioid receptor agonist Mesyl Sal B, a potent and long-acting analogue of salvinorin A.

Authors:  B Simonson; A S Morani; A W M Ewald; L Walker; N Kumar; D Simpson; J H Miller; T E Prisinzano; B M Kivell
Journal:  Br J Pharmacol       Date:  2014-07-01       Impact factor: 8.739
  7 in total

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