| Literature DB >> 2183415 |
J Klein1, J Gutknecht, N Fischer.
Abstract
Many alleles at the human major histocompatibility complex (HLA) loci diverged before the divergence of humans and great apes from a common ancestor. This fact puts a lower limit on the size of the bottleneck in human evolution: the genus Homo must have been founded by no less than ten and probably by more than 10,000 individuals.Entities:
Mesh:
Year: 1990 PMID: 2183415 DOI: 10.1016/0168-9525(90)90042-5
Source DB: PubMed Journal: Trends Genet ISSN: 0168-9525 Impact factor: 11.639