Literature DB >> 21833810

Development of a new hanging-type esophageal stent for preventing migration: a preliminary study in an animal model of esophagotracheal fistula.

Masayuki Endo1, Toshio Kaminou, Yasufumi Ohuchi, Kimihiko Sugiura, Shinsaku Yata, Akira Adachi, Tsuyoshi Kawai, Syohei Takasugi, Shuichi Yamamoto, Kensuke Matsumoto, Masayuki Hashimoto, Takashi Ihaya, Toshihide Ogawa.   

Abstract

PURPOSE: Covered, self-expandable metallic stents (SEMS) have been enthusiastically adopted for the treatment of esophagotracheal fistula, but problems with stent migration have yet to be resolved. To overcome this problem, we have developed a new hanging-type esophageal stent designed to prevent migration, and we conducted an animal study to assess the efficacy of our method.
METHODS: A total of six female pigs were used in this study. The main characteristic of our stent was the presence of a string tied to the proximal edge of the stent for fixation under the skin of the neck. The first experiment was performed to confirm technical feasibility in three pigs with esophagotracheal fistula. The second experiment was performed to evaluate stent migration and esophagotracheal fistula in three pigs.
RESULTS: Creation of the esophagotracheal fistula and stent placement were technically successful in all pigs. In the first experiment, esophagotracheal fistula was sealed by stent placement. In the second experiment, no stent migration was seen 11 or 12 days after stent placement. Gross findings showed no fistulas on the esophageal or tracheal wall.
CONCLUSIONS: Our new hanging-type esophageal stent seems to offer a feasible method for preventing stent migration.

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Year:  2011        PMID: 21833810     DOI: 10.1007/s00270-011-0240-9

Source DB:  PubMed          Journal:  Cardiovasc Intervent Radiol        ISSN: 0174-1551            Impact factor:   2.740


  2 in total

1.  Establishing a rabbit model of malignant esophagostenosis using the endoscopic implantation technique for studies on stent innovation.

Authors:  Jin Huang; Jinquan Shuang; Guanyin Xiong; Xiang Wang; Yin Zhang; Xiaowei Tang; Zhining Fan; Yingzhou Shen; Hanming Song; Zhi Liu
Journal:  J Transl Med       Date:  2014-02-10       Impact factor: 5.531

2.  Efficacy of Retrievable Metallic Stent with Fixation String for Benign Stricture after Upper Gastrointestinal Surgery.

Authors:  Jeong-Eun Kim; Hyo-Cheol Kim; Myungsu Lee; Saebeom Hur; Minuk Kim; Sang Hwan Lee; Soo Buem Cho; Chan Sun Kim; Joon Koo Han
Journal:  Korean J Radiol       Date:  2016-10-31       Impact factor: 3.500

  2 in total

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