Literature DB >> 21833411

N-heterocyclic carbene-catalyzed aza-Michael addition.

Qiang Kang1, Yugen Zhang.   

Abstract

Aza-Michael addition of amines, including aromatic and aliphatic amines, with α, β-unsaturated ketones was realized employing N-Heterocyclic Carbene (NHC) as organocatalyst, yielding β-amino ketones with up to 98% yield.

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Year:  2011        PMID： 21833411     DOI： 10.1039/c1ob05429e

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  4 in total

Review 1.  Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes.

Authors:  Darrin M Flanigan; Fedor Romanov-Michailidis; Nicholas A White; Tomislav Rovis
Journal:  Chem Rev       Date:  2015-05-20       Impact factor: 60.622

2.  Accelerated C-N bond formation in dropcast thin films on ambient surfaces.

Authors:  Abraham K Badu-Tawiah; Dahlia I Campbell; R Graham Cooks
Journal:  J Am Soc Mass Spectrom       Date:  2012-07-24       Impact factor: 3.109

3.  Highly enantioselective sulfa-Michael addition reactions using N-heterocyclic carbene as a non-covalent organocatalyst.

Authors:  Jiean Chen; Sixuan Meng; Leming Wang; Hongmei Tang; Yong Huang
Journal:  Chem Sci       Date:  2015-04-23       Impact factor: 9.825

4.  N-Heterocyclic carbenes as chiral Brønsted base catalysts: a highly diastereo- and enantioselective 1,6-addition reaction.

Authors:  Surojit Santra; Arka Porey; Barun Jana; Joyram Guin
Journal:  Chem Sci       Date:  2018-07-02       Impact factor: 9.825
  4 in total

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