Literature DB >> 21832115

The urokinase plasminogen activator system in metastatic papillary thyroid carcinoma: a potential therapeutic target.

Theodore S Nowicki1, Augustine L Moscatello, Edward Shin, Stimson Schantz, Raj K Tiwari, Jan Geliebter.   

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Year:  2011        PMID: 21832115      PMCID: PMC3417282          DOI: 10.1210/jc.2011-1123

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN: 0021-972X            Impact factor:   5.958


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  11 in total

1.  Mitochondrial localization and regulation of BRAFV600E in thyroid cancer: a clinically used RAF inhibitor is unable to block the mitochondrial activities of BRAFV600E.

Authors:  Min Hee Lee; Seong Eun Lee; Dong Wook Kim; Min Jeong Ryu; Sung Jin Kim; Sung Joong Kim; Yong Kyoung Kim; Ji Hoon Park; Gi Ryang Kweon; Jin Man Kim; Jung Uee Lee; Valentina De Falco; Young Suk Jo; Minho Shong
Journal:  J Clin Endocrinol Metab       Date:  2010-10-06       Impact factor: 5.958

2.  The Oral Serine Protease Inhibitor WX-671 - First Experience in Patients with Advanced Head and Neck Carcinoma.

Authors:  Jens E Meyer; Carsten Brocks; Hendrik Graefe; Carola Mala; Natalie Thäns; Markus Bürgle; Annette Rempel; Nicole Rotter; Barbara Wollenberg; Stephan Lang
Journal:  Breast Care (Basel)       Date:  2008-10-16       Impact factor: 2.860

3.  Drug discovery: inhibitors that activate.

Authors:  Karen Cichowski; Pasi A Jänne
Journal:  Nature       Date:  2010-03-18       Impact factor: 49.962

4.  Long-term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma: benefits and limits of radioiodine therapy.

Authors:  C Durante; N Haddy; E Baudin; S Leboulleux; D Hartl; J P Travagli; B Caillou; M Ricard; J D Lumbroso; F De Vathaire; M Schlumberger
Journal:  J Clin Endocrinol Metab       Date:  2006-05-09       Impact factor: 5.958

5.  Inhibition of uPAR and uPA reduces invasion in papillary thyroid carcinoma cells.

Authors:  Theodore S Nowicki; Nicolas T Kummer; Codrin Iacob; Nina Suslina; Steven Schaefer; Stimson Schantz; Edward Shin; Augustine L Moscatello; Raj K Tiwari; Jan Geliebter
Journal:  Laryngoscope       Date:  2010-07       Impact factor: 3.325

6.  Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: the M. D. Anderson experience.

Authors:  Maria E Cabanillas; Steven G Waguespack; Yulia Bronstein; Michelle D Williams; Lei Feng; Mike Hernandez; Adriana Lopez; Steven I Sherman; Naifa L Busaidy
Journal:  J Clin Endocrinol Metab       Date:  2010-04-14       Impact factor: 5.958

Review 7.  Regulation of cell signalling by uPAR.

Authors:  Harvey W Smith; Chris J Marshall
Journal:  Nat Rev Mol Cell Biol       Date:  2010-01       Impact factor: 94.444

8.  Downregulation of uPAR inhibits migration, invasion, proliferation, FAK/PI3K/Akt signaling and induces senescence in papillary thyroid carcinoma cells.

Authors:  Theodore S Nowicki; Hong Zhao; Zbigniew Darzynkiewicz; Augustine Moscatello; Edward Shin; Stimson Schantz; Raj K Tiwari; Jan Geliebter
Journal:  Cell Cycle       Date:  2011-01-01       Impact factor: 4.534

9.  Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with sorafenib.

Authors:  Zita Dubauskas; Joy Kunishige; Victor G Prieto; Eric Jonasch; Patrick Hwu; Nizar M Tannir
Journal:  Clin Genitourin Cancer       Date:  2009-01       Impact factor: 2.872

10.  Fragment-based discovery of mexiletine derivatives as orally bioavailable inhibitors of urokinase-type plasminogen activator.

Authors:  Martyn Frederickson; Owen Callaghan; Gianni Chessari; Miles Congreve; Suzanna R Cowan; Julia E Matthews; Rachel McMenamin; Donna-Michelle Smith; Mladen Vinković; Nicola G Wallis
Journal:  J Med Chem       Date:  2007-12-29       Impact factor: 7.446

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