Literature DB >> 2183079

Effect of immunomodulator thymopentin on impaired seroresponse to influenza vaccine in patients on haemodialysis.

W E Beyer1, T C Noordzij, P Kramer, P P Diderich, C T Op den Hoek, J Janssen, N Masurel, W Weimar.   

Abstract

In a double-blind placebo-controlled multicentre study, the effect of the immunomodulator thymopentin (TP5) on the antibody production to trivalent influenza vaccine was tested in 108 patients on chronic intermittent haemodialysis (HD). Antibody production was determined in pre- and postvaccination sera. Compared to a group of 35 young healthy adult control subjects, HD patients showed a clearly impaired seroresponsiveness to all three vaccine components, regardless of treatment with TP5 or placebo. We conclude that TP5 administration is not able to enhance humoral immunity in patients on chronic intermittent HD.

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Year:  1990        PMID： 2183079     DOI： 10.1159/000185883

Source DB:  PubMed          Journal:  Nephron        ISSN： 1660-8151            Impact factor:   2.847


  6 in total

Review 1.  Influenza vaccines. A reappraisal of their use.

Authors:  A M Palache
Journal:  Drugs       Date:  1997-12       Impact factor: 9.546

Review 2.  The use of vaccines in renal failure.

Authors:  D W Johnson; S J Fleming
Journal:  Clin Pharmacokinet       Date:  1992-06       Impact factor: 6.447

3.  Evaluation of influenza virus A/H3N2 and B vaccines on the basis of cross-reactivity of postvaccination human serum antibodies against influenza viruses A/H3N2 and B isolated in MDCK cells and embryonated hen eggs.

Authors:  Noriko Kishida; Seiichiro Fujisaki; Masaru Yokoyama; Hironori Sato; Reiko Saito; Hideyuki Ikematsu; Hong Xu; Emi Takashita; Masato Tashiro; Shinichi Takao; Takuya Yano; Tomoko Suga; Chiharu Kawakami; Miwako Yamamoto; Keiko Kajiyama; Hiroyuki Saito; Shin'ichi Shimada; Sumi Watanabe; Satomi Aoki; Katsuya Taira; Miyako Kon; Jih-Hui Lin; Takato Odagiri
Journal:  Clin Vaccine Immunol       Date:  2012-04-04

4.  Immune response to influenza vaccination in children with renal disease.

Authors:  S L Furth; A M Neu; S A McColley; B Case; M Steinhoff; B Fivush
Journal:  Pediatr Nephrol       Date:  1995-10       Impact factor: 3.714

5.  Antibody response to influenza A vaccination in children with nephrotic syndrome.

Authors:  Hakan M Poyrazoğlu; Ruhan Düşünsel; Zübeyde Gündüz; Türkan Patiroğlu; Selmin Köklü
Journal:  Pediatr Nephrol       Date:  2003-11-25       Impact factor: 3.714

6.  Influenza virus vaccination in pediatric nephrotic syndrome significantly reduces rate of relapse and influenza virus infection as assessed in a nationwide survey.

Authors:  Shingo Ishimori; Takashi Ando; Kaori Kikunaga; Chikako Terano; Mai Sato; Fumiyo Komaki; Riku Hamada; Yuko Hamasaki; Yoshinori Araki; Yoshimitsu Gotoh; Koichi Nakanishi; Hitoshi Nakazato; Takeshi Matsuyama; Kazumoto Iijima; Norishige Yoshikawa; Shuichi Ito; Masataka Honda; Kenji Ishikura
Journal:  Sci Rep       Date:  2021-12-02       Impact factor: 4.379
  6 in total

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