Literature DB >> 2183001

Molecular analysis of the mitochondrial transcription factor mtf2 of Saccharomyces cerevisiae.

T Lisowsky1.   

Abstract

The nuclear gene for a new mitochondrial transcription factor (mtf2) was isolated by transformation of mutant pet-ts3504. It was localized on a 6.4 kb fragment of yeast genomic DNA by subcloning and complementation tests. Sequencing of a 1.7 kb DNA fragment revealed an open reading frame of 1320 bp. A transcript of 1400 nucleotides can be assigned to this region. Gene disruption of this reading frame in a wild-type yeast strain created a stable pet phenotype. Further analysis of this insertion mutation showed that it is allelic to the mutated gene of pet-ts3504. Comparison of the 5' upstream regions of MTF2 and a previously characterized mitochondrial transcription factor (MTF1) revealed common sequence motifs which may be important for coordinated regulation of gene expression.

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Year:  1990        PMID： 2183001     DOI： 10.1007/BF00260480

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN： 0026-8925


  31 in total

1.  Steady state analysis of mitochondrial RNA after growth of yeast Saccharomyces cerevisiae under catabolite repression and derepression.

Authors:  D M Mueller; G S Getz
Journal:  J Biol Chem       Date:  1986-09-05       Impact factor: 5.157

2.  Isolation of the nuclear gene encoding a subunit of the yeast mitochondrial RNA polymerase.

Authors:  J L Kelly; A L Greenleaf; I R Lehman
Journal:  J Biol Chem       Date:  1986-08-05       Impact factor: 5.157

3.  Improved tools for biological sequence comparison.

Authors:  W R Pearson; D J Lipman
Journal:  Proc Natl Acad Sci U S A       Date:  1988-04       Impact factor: 11.205

4.  Formation of merodiploids in matings with a class of Rec- recipient strains of Escherichia coli K12.

Authors:  B Low
Journal:  Proc Natl Acad Sci U S A       Date:  1968-05       Impact factor: 11.205

5.  Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.

Authors:  H Aviv; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1972-06       Impact factor: 11.205

6.  A system for shotgun DNA sequencing.

Authors:  J Messing; R Crea; P H Seeburg
Journal:  Nucleic Acids Res       Date:  1981-01-24       Impact factor: 16.971

7.  The structure of transposable yeast mating type loci.

Authors:  K A Nasmyth; K Tatchell
Journal:  Cell       Date:  1980-03       Impact factor: 41.582

8.  Mutations in the genes for mitochondrial RNA polymerase and a second mitochondrial transcription factor of Saccharomyces cerevisiae.

Authors:  T Lisowsky; G Michaelis
Journal:  Mol Gen Genet       Date:  1989-10

9.  Temperature sensitive pet mutants in yeast Saccharomyces cerevisiae that lose mitochondrial RNA.

Authors:  D M Mueller; T K Biswas; J Backer; J C Edwards; M Rabinowitz; G S Getz
Journal:  Curr Genet       Date:  1987       Impact factor: 3.886

10.  Evidence for an intron-contained sequence required for the splicing of yeast RNA polymerase II transcripts.

Authors:  C J Langford; D Gallwitz
Journal:  Cell       Date:  1983-06       Impact factor: 41.582
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  8 in total

1.  Compilation of sequence-specific DNA-binding proteins implicated in transcriptional control in fungi.

Authors:  S S Dhawale; A C Lane
Journal:  Nucleic Acids Res       Date:  1993-12-11       Impact factor: 16.971

Review 2.  PET genes of Saccharomyces cerevisiae.

Authors:  A Tzagoloff; C L Dieckmann
Journal:  Microbiol Rev       Date:  1990-09

3.  Regulation of mitochondrial transcription during the stringent response in yeast.

Authors:  R Cantwell; C M McEntee; A P Hudson
Journal:  Curr Genet       Date:  1992-03       Impact factor: 3.886

4.  Change of serine309 into proline causes temperature sensitivity of the nuclear NAM1/MTF2 gene product for yeast mitochondria.

Authors:  T Lisowsky; G Riemen; G Michaelis
Journal:  Nucleic Acids Res       Date:  1990-12-11       Impact factor: 16.971

5.  The NAM1/MTF2 nuclear gene product is selectively required for the stability and/or processing of mitochondrial transcripts of the atp6 and of the mosaic, cox1 and cytb genes in Saccharomyces cerevisiae.

Authors:  O Groudinsky; I Bousquet; M G Wallis; P P Slonimski; G Dujardin
Journal:  Mol Gen Genet       Date:  1993-09

6.  Multiple interactions involving the amino-terminal domain of yeast mtRNA polymerase determine the efficiency of mitochondrial protein synthesis.

Authors:  Matthew S Rodeheffer; Gerald S Shadel
Journal:  J Biol Chem       Date:  2003-03-10       Impact factor: 5.157

Review 7.  Genetic approaches to the study of mitochondrial biogenesis in yeast.

Authors:  M Bolotin-Fukuhara; L A Grivell
Journal:  Antonie Van Leeuwenhoek       Date:  1992-08       Impact factor: 2.271

8.  The product of the nuclear gene PET309 is required for translation of mature mRNA and stability or production of intron-containing RNAs derived from the mitochondrial COX1 locus of Saccharomyces cerevisiae.

Authors:  G M Manthey; J E McEwen
Journal:  EMBO J       Date:  1995-08-15       Impact factor: 11.598
  8 in total

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