Literature DB >> 21827631

Non-healing leg ulcers in a patient with dystrophic calcification and crest syndrome: a challenging clinical case.

Mahmoud Al-Najjar1, Mark J Jackson.   

Abstract

The management of non-healing leg ulcers in patients with CREST syndrome and subdermal calcification is rarely reported in medical literature. Only one similar case was found in the literature (1). Dealing with such patients can be a challenge for wound specialists. In this article, we discuss the clinical progress of an interesting case of extensive non-healing leg ulcers in a CREST patient with dystrophic calcification. The combination of systemic physiological deficits and immune compromise, along with the local physical abnormalities associated with the wound pose a complex multifactorial aetiological mix. There is no conclusive data on the optimal management of these wounds in CREST patients. It seems that ablation of the calcific deposits may offer some hope.
© 2011 The Authors. © 2011 Blackwell Publishing Ltd and Medicalhelplines.com Inc.

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Year:  2011        PMID: 21827631      PMCID: PMC7950557          DOI: 10.1111/j.1742-481X.2011.00834.x

Source DB:  PubMed          Journal:  Int Wound J        ISSN: 1742-4801            Impact factor:   3.315


  9 in total

1.  Surgical removal of ulcer and lipodermatosclerosis followed by split-skin grafting (shave therapy) yields good long-term results in "non-healing" venous leg ulcers.

Authors:  W Schmeller; Y Gaber
Journal:  Acta Derm Venereol       Date:  2000 Jul-Aug       Impact factor: 4.437

2.  Dystrophic calcification as a cause for non healing leg ulcers.

Authors:  Stuart Enoch; Susanne Kupitz; David R Miller; Keith G Harding
Journal:  Int Wound J       Date:  2005-06       Impact factor: 3.315

3.  Clinical significance of subcutaneous calcinosis in patients with systemic sclerosis. Does diltiazem induce its regression?

Authors:  M Vayssairat; D Hidouche; N Abdoucheli-Baudot; J P Gaitz
Journal:  Ann Rheum Dis       Date:  1998-04       Impact factor: 19.103

4.  Subcutaneous calcification of the lower limbs.

Authors:  I Peled; A Bar-Lev; M R Wexler
Journal:  Ann Plast Surg       Date:  1982-04       Impact factor: 1.539

5.  Electric shock wave lithotripsy (ESWL) as a pain control measure in dermatomyositis with calcinosis cutis-old method, new discovery.

Authors:  Alice Y K Chan; Edmund Li
Journal:  Clin Rheumatol       Date:  2004-11-24       Impact factor: 2.980

6.  Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shock wave lithotripsy.

Authors:  Agnès Sparsa; Nicolas Lesaux; Emmanuel Kessler; Jean-Marie Bonnetblanc; Sophie Blaise; Valérie Lebrun-Ly; Pierre Colombeau; Elisabeth Vidal; Christophe Bédane
Journal:  J Am Acad Dermatol       Date:  2005-11       Impact factor: 11.527

Review 7.  Calcifying disorders of the skin.

Authors:  J S Walsh; J A Fairley
Journal:  J Am Acad Dermatol       Date:  1995-11       Impact factor: 11.527

8.  Shave therapy is a simple, effective treatment of persistent venous leg ulcers.

Authors:  W Schmeller; Y Gaber; H B Gehl
Journal:  J Am Acad Dermatol       Date:  1998-08       Impact factor: 11.527

9.  Subcutaneous calcification in venous ulcers: report of a case.

Authors:  A L Pathy; V Rae; V Falanga
Journal:  J Dermatol Surg Oncol       Date:  1990-05
  9 in total
  3 in total

Review 1.  Dystrophic calcinosis with both a huge calcified mass in the cervical spine and calcification in the chest wall in a patient with rheumatoid overlap syndrome.

Authors:  Tadashi Nakamura; Kei Hirakawa; Hirokazu Takaoka; Ken-Ichi Iyama
Journal:  Clin Rheumatol       Date:  2014-06-04       Impact factor: 2.980

2.  Dystrophic calcinosis in a patient with overlap syndrome (scleroderma and rheumatoid arthritis) treated by leflunomide: A case report.

Authors:  Sang Yeob Lee; Sung Won Lee; Won Tae Chung
Journal:  Medicine (Baltimore)       Date:  2018-11       Impact factor: 1.889

3.  Microangiopathy in Inflammatory Diseases-Strategies in Surgery of the Lower Extremity.

Authors:  Christoph Biehl; Lotta Biehl; Ingo Helmut Tarner; Ulf Müller-Ladner; Christian Heiss; Martin Heinrich
Journal:  Life (Basel)       Date:  2022-01-28
  3 in total

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