Literature DB >> 21827311

Risk for suicidal ideation among the offspring of bipolar parents: results from the Bipolar Offspring Study (BIOS).

Tina R Goldstein1, Mihaela Obreja, Wael Shamseddeen, Satish Iyengar, David A Axelson, Benjamin I Goldstein, Kelly Monk, Mary Beth Hickey, Dara Sakolsky, David J Kupfer, David A Brent, Boris Birmaher.   

Abstract

The objective of the study was to examine rates and identify risk factors for suicidal ideation among offspring of parents with bipolar disorder. Subjects included 388 offspring of parents with bipolar disorder and 250 offspring of matched community controls enrolled in the Pittsburgh Bipolar Offspring Study (BIOS). Offspring of bipolar probands displayed greater rates of lifetime suicidal ideation than offspring of controls (33% versus 20%). Factors most strongly associated with lifetime suicidal ideation in offspring of bipolar parents included offspring mood disorder, hostility, recent sexual abuse, and family conflict. Offspring of parents with bipolar disorder are at elevated risk for suicidal ideation as compared with offspring of controls. Suicide risk assessment in this population should attend to specific risk factors identified.

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Mesh：

Year:  2011        PMID： 21827311      PMCID： PMC3361710          DOI： 10.1080/13811118.2011.589699

Source DB:  PubMed          Journal:  Arch Suicide Res        ISSN： 1381-1118


  57 in total

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4.  Toward the Definition of a Bipolar Prodrome: Dimensional Predictors of Bipolar Spectrum Disorders in At-Risk Youths.

Authors:  Danella M Hafeman; John Merranko; David Axelson; Benjamin I Goldstein; Tina Goldstein; Kelly Monk; Mary Beth Hickey; Dara Sakolsky; Rasim Diler; Satish Iyengar; David Brent; David Kupfer; Boris Birmaher
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7.  Risk factors for pre-adolescent onset suicidal behavior in a high-risk sample of youth.

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10.  Assessment of a Person-Level Risk Calculator to Predict New-Onset Bipolar Spectrum Disorder in Youth at Familial Risk.

Authors:  Danella M Hafeman; John Merranko; Tina R Goldstein; David Axelson; Benjamin I Goldstein; Kelly Monk; Mary Beth Hickey; Dara Sakolsky; Rasim Diler; Satish Iyengar; David A Brent; David J Kupfer; Michael W Kattan; Boris Birmaher
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