Literature DB >> 21824952

Predialysis nephrology care of older patients approaching end-stage renal disease.

Wolfgang C Winkelmayer1, Jun Liu, Glenn M Chertow, Manjula Kurella Tamura.   

Abstract

BACKGROUND: Little is known about trends in the timing of first nephrology consultation and associated outcomes among older patients initiating dialysis.
METHODS: Data from patients aged 67 years or older who initiated dialysis in the United States between January 1, 1996, and December 31, 2006, were stratified by timing of the earliest identifiable nephrology visit. Trends of earlier nephrology consultation were formally examined in light of concurrently changing case mix and juxtaposed with trends in 1-year mortality rates after initiation of dialysis.
RESULTS: Among 323,977 older patients initiating dialysis, the proportion of patients receiving nephrology care less than 3 months before initiation of dialysis decreased from 49.6% (in 1996) to 34.7% (in 2006). Patients initiated dialysis with increasingly preserved kidney function, from a mean estimated glomerular filtration rate of 8 mL/min/1.73 m(2) in 1996 to 12 mL/min/1.73 m(2) in 2006. Patients were less anemic in later years, which was partly attributable to increased use of erythropoiesis-stimulating agents, and fewer used peritoneal dialysis as the initial modality. During the same period, crude 1-year mortality rates remained unchanged (annual change in mortality rate, +0.2%; 95% confidence interval, 0% to +0.4%). Adjustment for changes in demographic and comorbidity patterns yielded estimated annual reductions in 1-year mortality rates of 0.9% (95% confidence interval, 0.7% to 1.1%), which were explained only partly by concurrent trends toward earlier nephrology consultation (annual mortality reduction after accounting for timing of nephrology care was attenuated to 0.4% [0.2% to 0.6%]).
CONCLUSIONS: Despite significant trends toward earlier use of nephrology consultation among older patients approaching maintenance dialysis, we observed no material improvement in 1-year survival rates after dialysis initiation during the same time period.

Entities:  

Mesh:

Year:  2011        PMID: 21824952      PMCID: PMC4123329          DOI: 10.1001/archinternmed.2011.360

Source DB:  PubMed          Journal:  Arch Intern Med        ISSN: 0003-9926


  35 in total

1.  Late referral and modality choice in end-stage renal disease.

Authors:  W C Winkelmayer; R J Glynn; R Levin; W Owen; J Avorn
Journal:  Kidney Int       Date:  2001-10       Impact factor: 10.612

2.  Determinants of type and timing of initial permanent hemodialysis vascular access.

Authors:  C O Stehman-Breen; D J Sherrard; D Gillen; M Caps
Journal:  Kidney Int       Date:  2000-02       Impact factor: 10.612

3.  Validation of comorbid conditions on the end-stage renal disease medical evidence report: the CHOICE study. Choices for Healthy Outcomes in Caring for ESRD.

Authors:  J Craig Longenecker; Josef Coresh; Michael J Klag; Andrew S Levey; Alice A Martin; Nancy E Fink; Neil R Powe
Journal:  J Am Soc Nephrol       Date:  2000-03       Impact factor: 10.121

4.  Reporting estimated GFR: a laboratory perspective.

Authors:  W Greg Miller
Journal:  Am J Kidney Dis       Date:  2008-10       Impact factor: 8.860

5.  Timing of nephrologist referral and arteriovenous access use: the CHOICE Study.

Authors:  B C Astor; J A Eustace; N R Powe; M J Klag; J H Sadler; N E Fink; J Coresh
Journal:  Am J Kidney Dis       Date:  2001-09       Impact factor: 8.860

6.  Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis.

Authors:  Christoph Wanner; Vera Krane; Winfried März; Manfred Olschewski; Johannes F E Mann; Günther Ruf; Eberhard Ritz
Journal:  N Engl J Med       Date:  2005-07-21       Impact factor: 91.245

7.  Revascularization versus medical therapy for renal-artery stenosis.

Authors:  Keith Wheatley; Natalie Ives; Richard Gray; Philip A Kalra; Jonathan G Moss; Colin Baigent; Susan Carr; Nicholas Chalmers; David Eadington; George Hamilton; Graham Lipkin; Anthony Nicholson; John Scoble
Journal:  N Engl J Med       Date:  2009-11-12       Impact factor: 91.245

8.  A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease.

Authors:  Marc A Pfeffer; Emmanuel A Burdmann; Chao-Yin Chen; Mark E Cooper; Dick de Zeeuw; Kai-Uwe Eckardt; Jan M Feyzi; Peter Ivanovich; Reshma Kewalramani; Andrew S Levey; Eldrin F Lewis; Janet B McGill; John J V McMurray; Patrick Parfrey; Hans-Henrik Parving; Giuseppe Remuzzi; Ajay K Singh; Scott D Solomon; Robert Toto
Journal:  N Engl J Med       Date:  2009-10-30       Impact factor: 91.245

9.  Age affects outcomes in chronic kidney disease.

Authors:  Ann M O'Hare; Andy I Choi; Daniel Bertenthal; Peter Bacchetti; Amit X Garg; James S Kaufman; Louise C Walter; Kala M Mehta; Michael A Steinman; Michael Allon; William M McClellan; C Seth Landefeld
Journal:  J Am Soc Nephrol       Date:  2007-09-12       Impact factor: 10.121

10.  Rosuvastatin and cardiovascular events in patients undergoing hemodialysis.

Authors:  Bengt C Fellström; Alan G Jardine; Roland E Schmieder; Hallvard Holdaas; Kym Bannister; Jaap Beutler; Dong-Wan Chae; Alejandro Chevaile; Stuart M Cobbe; Carola Grönhagen-Riska; José J De Lima; Robert Lins; Gert Mayer; Alan W McMahon; Hans-Henrik Parving; Giuseppe Remuzzi; Ola Samuelsson; Sandor Sonkodi; D Sci; Gultekin Süleymanlar; Dimitrios Tsakiris; Vladimir Tesar; Vasil Todorov; Andrzej Wiecek; Rudolf P Wüthrich; Mattis Gottlow; Eva Johnsson; Faiez Zannad
Journal:  N Engl J Med       Date:  2009-03-30       Impact factor: 91.245

View more
  27 in total

1.  Are there alternatives to hemodialysis for the elderly patient with end-stage renal failure?

Authors:  Bjorg Thorsteinsdottir; Keith M Swetz; Molly A Feely; Paul S Mueller; Amy W Williams
Journal:  Mayo Clin Proc       Date:  2012-06       Impact factor: 7.616

2.  Aichi cohort study of the prognosis in patients newly initiated into dialysis (AICOPP): baseline characteristics and trends observed in diabetic nephropathy.

Authors:  Manabu Hishida; Hirofumi Tamai; Takatoshi Morinaga; Michitaka Maekawa; Takafumi Aoki; Hidetaka Tomida; Shintaro Komatsu; Tomoaki Kamiya; Shoichi Maruyama; Seiichi Matsuo; Daijo Inaguma
Journal:  Clin Exp Nephrol       Date:  2016-02-23       Impact factor: 2.801

Review 3.  Dialysis in the frail elderly--a current ethical problem, an impending ethical crisis.

Authors:  Bjorg Thorsteinsdottir; Keith M Swetz; Jon C Tilburt
Journal:  J Gen Intern Med       Date:  2013-05-18       Impact factor: 5.128

4.  Life Expectancy Gains for Patients with ESRD.

Authors:  Kirsten L Johansen
Journal:  Clin J Am Soc Nephrol       Date:  2017-12-14       Impact factor: 8.237

5.  Receipt of Nephrology Care and Clinical Outcomes Among Veterans With Advanced CKD.

Authors:  Enrica Fung; Tara I Chang; Glenn M Chertow; I-Chun Thomas; Steven M Asch; Manjula Kurella Tamura
Journal:  Am J Kidney Dis       Date:  2017-08-12       Impact factor: 8.860

Review 6.  Chronic kidney disease prediction is an inexact science: The concept of "progressors" and "nonprogressors".

Authors:  Macaulay Amechi Chukwukadibia Onuigbo; Nneoma Agbasi
Journal:  World J Nephrol       Date:  2014-08-06

7.  Influence of Nephrologist Care on Management and Outcomes in Adults with Chronic Kidney Disease.

Authors:  Ana C Ricardo; Jason A Roy; Kaixiang Tao; Arnold Alper; Jing Chen; Paul E Drawz; Jeffrey C Fink; Chi-Yuan Hsu; John W Kusek; Akinlolu Ojo; Martin Schreiber; Michael J Fischer
Journal:  J Gen Intern Med       Date:  2015-07-03       Impact factor: 5.128

8.  Association between Duration of Predialysis Care and Mortality after Dialysis Start.

Authors:  Ping Liu; Robert R Quinn; Matthew J Oliver; Paul E Ronksley; Brenda R Hemmelgarn; Hude Quan; Swapnil Hiremath; Aminu K Bello; Peter G Blake; Amit X Garg; John Johnson; Mauro Verrelli; James M Zacharias; Samar Abd ElHafeez; Marcello Tonelli; Pietro Ravani
Journal:  Clin J Am Soc Nephrol       Date:  2018-03-05       Impact factor: 8.237

9.  Trends in anemia care in older patients approaching end-stage renal disease in the United States (1995-2010).

Authors:  Wolfgang C Winkelmayer; Aya A Mitani; Benjamin A Goldstein; M Alan Brookhart; Glenn M Chertow
Journal:  JAMA Intern Med       Date:  2014-05       Impact factor: 21.873

10.  Association of physician care with mortality in Kidney Early Evaluation Program (KEEP) participants.

Authors:  Georges Saab; Shu-Cheng Chen; Suying Li; Andrew S Bomback; Adam T Whaley-Connell; Claudine T Jurkovitz; Keith C Norris; Peter A McCullough
Journal:  Am J Kidney Dis       Date:  2012-03       Impact factor: 8.860

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.