| Literature DB >> 21824783 |
Ruth Devakaram1, David StC Black, Katherine T Andrews, Gillian M Fisher, Rohan A Davis, Naresh Kumar.
Abstract
7-Methoxyflavenes and 5,7,8-trimethoxyflavenes were found to undergo stereoselective acid-catalyzed rearrangement to generate the benzopyrano[4,3-b]benzopyran ring system present in the natural product, dependensin. Dependensin and its analogs were subjected to antimalarial growth inhibition assays against Plasmodium falciparum and found to have IC(50) values ranging between 1.9 and 3.9 μM.Entities:
Mesh：
Substances：
Year: 2011 PMID： 21824783 DOI： 10.1016/j.bmc.2011.07.009
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641