Barron Emmanuelle1, Migeot Virginie2, Séby Fabienne3, Ingrand Isabelle4, Potin-Gautier Martine5, Legube Bernard6, Rabouan Sylvie7. 1. Université de Poitiers, Laboratoire de Chimie et Microbiologie de l'Eau, UMR CNRS 6008, 40, avenue du Recteur Pineau, 86022 Poitiers Cedex, France. Electronic address: emmanuelle.barron@u-bordeaux2.fr. 2. Université de Poitiers, Laboratoire de Chimie et Microbiologie de l'Eau, UMR CNRS 6008, 40, avenue du Recteur Pineau, 86022 Poitiers Cedex, France; Université de Poitiers, Faculté de Médecine et Pharmacie, 6 rue de la Milétrie, 86034 Poitiers Cedex, France. Electronic address: virginie.migeot@univ-poitiers.fr. 3. Ultra Traces Analyses Aquitaine, Hélioparc Pau Pyrénées, 2 avenue du Président Angot, 64053 Pau Cedex 9, France. 4. Université de Poitiers, Faculté de Médecine et Pharmacie, 6 rue de la Milétrie, 86034 Poitiers Cedex, France. 5. Université de Pau et de l'Adour, Equipe de Chimie Analytique Bio-Inorganique et Environnement, UMR CNRS/UPPA 5254, avenue de l'Université, 64000 Pau, France. 6. Université de Poitiers, Laboratoire de Chimie et Microbiologie de l'Eau, UMR CNRS 6008, 40, avenue du Recteur Pineau, 86022 Poitiers Cedex, France. 7. Université de Poitiers, Laboratoire de Chimie et Microbiologie de l'Eau, UMR CNRS 6008, 40, avenue du Recteur Pineau, 86022 Poitiers Cedex, France; Université de Poitiers, Faculté de Médecine et Pharmacie, 6 rue de la Milétrie, 86034 Poitiers Cedex, France.
Abstract
BACKGROUND: Selenium is an essential element which can be toxic if ingested in excessive quantities. The main human exposure is food. In addition, intake may be boosted by consumption drinking water containing unusual high selenium concentration. OBJECTIVE: We measured the individual selenium level of people exposed to selenium concentration in drinking water greater than the maximum recommended limit which is 10 μg/L. METHODS: We carried out a prospective cohort study on 80 adults (40 exposed subjects i.e. living in the involved area and 40 non-exposed ones i.e. living elsewhere) in western France. We used three different approaches: (1) direct measurement of ingested selenium by the duplicate portion method, (2) dietary reconstitution with a food frequency questionnaire (FFQ) and (3) evaluation of the individual selenium status by measuring the selenium content in toenail clippings. Analyses were performed by inductively coupled plasma-mass spectrometry. The association between toenail selenium concentration and area of residence was analyzed using linear regression with repeated measurements. RESULTS: We estimated selenium intake from FFQ at 64±14 μg/day for exposed subjects as opposed to 52±14 μg/day for the non-exposed ones. On the basis of 305 duplicate diet samples, average intake was estimated at 64±26 μg/day for exposed subjects. Area of residence (p=0.0030) and smoking (p=0.0054) were independently associated with toenail selenium concentration. CONCLUSION: Whatever method used for estimating selenium intake, the selenium level in this studied area with high selenium concentrated drinking water is much lower than in seleniferous areas.
BACKGROUND:Selenium is an essential element which can be toxic if ingested in excessive quantities. The main human exposure is food. In addition, intake may be boosted by consumption drinking water containing unusual high selenium concentration. OBJECTIVE: We measured the individual selenium level of people exposed to selenium concentration in drinking water greater than the maximum recommended limit which is 10 μg/L. METHODS: We carried out a prospective cohort study on 80 adults (40 exposed subjects i.e. living in the involved area and 40 non-exposed ones i.e. living elsewhere) in western France. We used three different approaches: (1) direct measurement of ingested selenium by the duplicate portion method, (2) dietary reconstitution with a food frequency questionnaire (FFQ) and (3) evaluation of the individual selenium status by measuring the selenium content in toenail clippings. Analyses were performed by inductively coupled plasma-mass spectrometry. The association between toenail selenium concentration and area of residence was analyzed using linear regression with repeated measurements. RESULTS: We estimated selenium intake from FFQ at 64±14 μg/day for exposed subjects as opposed to 52±14 μg/day for the non-exposed ones. On the basis of 305 duplicate diet samples, average intake was estimated at 64±26 μg/day for exposed subjects. Area of residence (p=0.0030) and smoking (p=0.0054) were independently associated with toenail selenium concentration. CONCLUSION: Whatever method used for estimating selenium intake, the selenium level in this studied area with high selenium concentrated drinking water is much lower than in seleniferous areas.
Authors: Dasong Yu; Dongli Liang; Lingming Lei; Rong Zhang; Xiaofeng Sun; Zhiqing Lin Journal: Environ Sci Pollut Res Int Date: 2015-03-18 Impact factor: 4.223
Authors: Enrique Gutiérrez-González; Esther García-Esquinas; Nerea Fernández de Larrea-Baz; Inmaculada Salcedo-Bellido; Ana Navas-Acien; Virginia Lope; José Luis Gómez-Ariza; Roberto Pastor; Marina Pollán; Beatriz Pérez-Gómez Journal: Environ Res Date: 2019-10-07 Impact factor: 8.431
Authors: Esther Humann-Ziehank; Philip C Tegtmeyer; Bjoern Seelig; Petra Roehrig; Martin Ganter Journal: Acta Vet Scand Date: 2013-11-19 Impact factor: 1.695