| Literature DB >> 21823621 |
Huangdi Feng1, Denis S Ermolat'ev, Gonghua Song, Erik V Van der Eycken.
Abstract
A novel and efficient microwave-assisted decarboxylative three-component coupling of a 2-oxoacetic acid, an amine, and an alkyne (OA(2)-coulpling) has been developed. This new multicomponent coupling constitutes an efficient approach for the synthesis of polysubstituted propargylamines in the presence of a catalytic amount of copper(I) catalyst.Entities:
Year: 2011 PMID： 21823621 DOI： 10.1021/jo2013725
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354